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Acute Development of Multiple Keratoacanthomas and Squamous Cell Carcinomas After Treatment with Infliximab

Overview
Specialty Dermatology
Date 2004 Apr 21
PMID 15097933
Citations 18
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Abstract

Infliximab, a chimeric mouse-human monoclonal antibody, blocks the action of tumor necrosis factor-alpha and is a highly effective treatment for several inflammatory disorders, including inflammatory bowel disease and rheumatoid arthritis. Although safety data are encouraging, immunosuppressive sequelae may result. We report the acute development of multiple squamous cell carcinomas and keratoacanthomas in a patient receiving infliximab for rheumatoid arthritis.

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