Alpha 2.0
Login Register
» Articles » PMID: 15040045

Clinical Value of Helicobacter Pylori Stool Antigen Test, ImmunoCard STAT HpSA, for Detecting H Pylori Infection

Overview
Journal World J Gastroenterol
Publisher Baishideng Publishing Group
Specialty Gastroenterology
Date 2004 Mar 25
PMID 15040045
Citations 13
Authors
Yi-Hui Li
Hong Guo
Peng-Bin Zhang
Xiao-Yan Zhao
Si-ping Da
Affiliations
Soon will be listed here.
Abstract

Aim: To evaluate the reliability of the Helicobacter pylori stool antigen test, ImmunoCard STAT HpSA, for detecting H pylori infection.

Methods: Stool specimens were collected from 53 patients who received upper endoscopy examination due to gastrointestinal symptoms. ImmunoCard STAT HpSA was used to detect H pylori stool antigens. H pylori infection was detected based on three different tests: the urease test, Warthin-Starry staining and culture. H pylori status was defined as positive when both the urease test and histology or culture alone was positive.

Results: Sensitivity, specificity, positive predictive and negative predictive values and the total accuracy of ImmunoCard STAT HpSA for the diagnosis of H pylori infection were 92.6% (25/27), 88.5% (23/26), 89.3% (25/28), 92% (23/25) and 90.6% (48/53), respectively.

Conclusion: The stool antigen test, ImmunoCard STAT HpSA, is a simple noninvasive and accurate test for the diagnosis of H pylori infection.

Citing Articles

Chinese Consensus Report on Family-Based Infection Control and Management (2021 Edition).

Ding S, Du Y, Lu H, Wang W, Cheng H, Chen S Gut. 2021; 71(2):238-253.

PMID: 34836916 PMC: 8762011. DOI: 10.1136/gutjnl-2021-325630.

Things We Do for No Reason™: Serum Serologic Helicobacter pylori Testing.

Xu A, Graham D J Hosp Med. 2021; 16(11):691-693.

PMID: 34328849 PMC: 8577700. DOI: 10.12788/jhm.3638.

Non-invasive diagnostic tests for Helicobacter pylori infection.

Best L, Takwoingi Y, Siddique S, Selladurai A, Gandhi A, Low B Cochrane Database Syst Rev. 2018; 3:CD012080.

PMID: 29543326 PMC: 6513531. DOI: 10.1002/14651858.CD012080.pub2.

In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules.

Li Y, Hu X, Ding D, Zou Y, Xu Y, Wang X Nat Commun. 2017; 8:15653.

PMID: 28643777 PMC: 5501158. DOI: 10.1038/ncomms15653.

Investigation of Helicobacter pylori antigen in stool samples of patients with upper gastrointestinal complaints.

Calik Z, Karamese M, Acar O, Karamese S, Dicle Y, Albayrak F Braz J Microbiol. 2016; 47(1):167-71.

PMID: 26887240 PMC: 4822757. DOI: 10.1016/j.bjm.2015.11.022.

References
1.
Vaira D, Malfertheiner P, Megraud F, Axon A, Deltenre M, Hirschl A . Diagnosis of Helicobacter pylori infection with a new non-invasive antigen-based assay. HpSA European study group. Lancet. 1999; 354(9172):30-3. DOI: 10.1016/s0140-6736(98)08103-3. View
2.
Manes G, Balzano A, Iaquinto G, Ricci C, Piccirillo M, Giardullo N . Accuracy of the stool antigen test in the diagnosis of Helicobacter pylori infection before treatment and in patients on omeprazole therapy. Aliment Pharmacol Ther. 2001; 15(1):73-9. DOI: 10.1046/j.1365-2036.2001.00907.x. View
3.
Wang K, Wang X, Peng J, Cui Y, Wang J, Li C . Detection of serum anti-Helicobacter pylori immunoglobulin G in patients with different digestive malignant tumors. World J Gastroenterol. 2003; 9(11):2501-4. PMC: 4656528. DOI: 10.3748/wjg.v9.i11.2501. View
4.
Peitz U, Leodolter A, Kahl S, Agha-Amiri K, Wex T, Wolle K . Antigen stool test for assessment of Helicobacter pylori infection in patients with upper gastrointestinal bleeding. Aliment Pharmacol Ther. 2003; 17(8):1075-84. DOI: 10.1046/j.1365-2036.2003.01548.x. View
5.
van Leerdam M, van der Ende A, Ten Kate F, Rauws E, Tytgat G . Lack of accuracy of the noninvasive Helicobacter pylori stool antigen test in patients with gastroduodenal ulcer bleeding. Am J Gastroenterol. 2003; 98(4):798-801. DOI: 10.1111/j.1572-0241.2003.07387.x. View