Characterization of Six Type A Strains of Clostridium Botulinum That Contain Type B Toxin Gene Sequences

Overview

Journal FEMS Microbiol Lett

Publisher Oxford University Press

Specialty Microbiology

Date 2004 Feb 28

PMID 14987759

Citations 11

Authors

Nameer Kirma

Joseph L Ferreira

Barbara R Baumstark

Affiliations

Soon will be listed here.

Abstract

Six Clostridium botulinum isolates exhibiting type A toxicity as measured by the mouse bioassay were found to contain both type A and type B neurotoxin DNA sequences. The six strains were divided into three groups based on the DNA sequence of the type B neurotoxin gene. Members of each group exhibited 100% sequence identity over the 3876 bp type B toxin open reading frame. The type B toxin sequence of all groups differed at more than 60 positions when compared to the BGB control strain.

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