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Overgrowth and Pruning of Dendrites in Adult Rats Recovering from Neocortical Damage

Overview
Journal Brain Res
Specialty Neurology
Date 1992 May 22
PMID 1498666
Citations 101
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Abstract

Unilateral lesions to the forelimb representation (FL) area of the rat sensorimotor cortex caused a time-dependent increase in the dendritic arborization of layer V pyramidal neurons in the contralateral homotopic cortex. The increase in arborization was maximum at 2-3 weeks after the lesion, following which there was a partial reduction in dendritic branching. These neural morphological changes may be related to post-lesion behavioral changes in the use of the forelimbs.

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