MR Imaging of the Pituitary Gland in Central Precocious Puberty

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 1992 Jan 1

PMID 1491902

Citations 4

Authors

S C Kao

J S Cook

J R Hansen

T M Simonson

Affiliations

Soon will be listed here.

Abstract

Cranial magnetic resonance imaging was performed in 17 children with central precocious puberty (CPP) and 19 aged-matched controls to compare the appearance of the pituitary gland. Gland size was measured on T1-weighted sagittal and coronal images. The gland was graded according to the concavity or convexity of the upper surface, and the signal intensity of the gland was assessed visually. The mean pituitary volume in 13 CPP children without hypothalamic tumor (292.6 mm3) was significantly greater than that in normal controls (181.35 mm3). The mean volume for the four CPP children with hypothalamic tumor was smaller (145.0 mm3). Compared to controls, the upper pituitary surface in CPP patients appeared convex in a higher proportion. The anterior pituitary was isointense to pons in all patients and controls. Although the posterior pituitary bright spot was present in 14 controls and 11 CPP patients, none with hypothalamic tumor showed it.

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Cranial MRI scans are indicated in all girls with central precocious puberty.

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