Hypoglycemic Activity of Olive Leaf

Overview

Journal Planta Med

Specialty Biology

Date 1992 Dec 1

PMID 1484890

Citations 29

Authors

M Gonzalez

A Zarzuelo

M J Gamez

M P Utrilla

J Jimenez

I Osuna

Affiliations

Soon will be listed here.

Abstract

The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidiabetic activity in animals with alloxan-induced diabetes. The hypoglycemic activity of this compound may result from two mechanisms: (a) potentiation of glucose-induced insulin release, and (b) increased peripheral uptake of glucose.

Citing Articles

From by-products to new application opportunities: the enhancement of the leaves deriving from the fruit plants for new potential healthy products.

Regolo L, Giampieri F, Battino M, Armas Diaz Y, Mezzetti B, Elexpuru-Zabaleta M Front Nutr. 2024; 11:1083759.

PMID: 38895662 PMC: 11184148. DOI: 10.3389/fnut.2024.1083759.

Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review.

Selim S, Albqmi M, Al-Sanea M, Alnusaire T, Almuhayawi M, AbdElgawad H Front Nutr. 2022; 9:1008349.

PMID: 36424930 PMC: 9678927. DOI: 10.3389/fnut.2022.1008349.

Green and Non-conventional Extraction of Bioactive Compounds from Olive Leaves: Screening of Novel Natural Deep Eutectic Solvents and Investigation of Process Parameters.

Unlu A Waste Biomass Valorization. 2021; 12(10):5329-5346.

PMID: 33727990 PMC: 7953197. DOI: 10.1007/s12649-021-01411-3.

Antimicrobial effect of different herbal plant extracts against different microbial population.

Hemeg H, Moussa I, Ibrahim S, Dawoud T, Alhaji J, Mubarak A Saudi J Biol Sci. 2020; 27(12):3221-3227.

PMID: 33304127 PMC: 7714981. DOI: 10.1016/j.sjbs.2020.08.015.

The effect of olive leaf extract on cardiovascular health markers: a randomized placebo-controlled clinical trial.

Stevens Y, Winkens B, Jonkers D, Masclee A Eur J Nutr. 2020; 60(4):2111-2120.

PMID: 33034707 PMC: 8137474. DOI: 10.1007/s00394-020-02397-9.