Effect of Methylphenidate on Time Perception in Children with Attention-deficit/hyperactivity Disorder

Overview

Journal Exp Clin Psychopharmacol

Publisher American Psychological Association

Specialty Pharmacology

Date 2004 Feb 11

PMID 14769100

Citations 18

Authors

Ronald L Baldwin

John J Chelonis

Rebecca A Flake

Mark C Edwards

Charles R Feild

Julie B Meaux

Merle G Paule

Affiliations

Soon will be listed here.

Abstract

The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effect on the number of correct responses or on the mean duration of lever holds. MPH administration significantly decreased timing response variability, increased holds of 10- to 11-s duration, and decreased lever holds of extremely short durations. These results indicate that administration of MPH resulted in more precise timing performance without changing the mean duration of lever holds, suggesting an enhancement in working memory.

Citing Articles

Attention-Deficit/Hyperactivity Disorder (ADHD) and Time Perception in Adults: Do Adults with Different ADHD Symptomatology Severity Perceive Time Differently? Findings from the National Czech Study.

Ptacek R, Vnukova M, Dechterenko F, Weissenberger S, Kitzlerova E, Ptackova H Med Sci Monit. 2022; 28:e936849.

PMID: 35841140 PMC: 9297734. DOI: 10.12659/MSM.936849.

Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children.

Merced-Nieves F, Chelonis J, Pantic I, Schnass L, Tellez-Rojo M, Braun J Neurotoxicol Teratol. 2022; 90:107075.

PMID: 35108597 PMC: 8957713. DOI: 10.1016/j.ntt.2022.107075.

An evaluation of the effect of methylphenidate on working memory, time perception, and choice impulsivity in children with ADHD.

Campez M, Raiker J, Little K, Altszuler A, Merrill B, Macphee F Exp Clin Psychopharmacol. 2021; 30(2):209-219.

PMID: 33475395 PMC: 8406432. DOI: 10.1037/pha0000446.

A time-based intervention to treat impulsivity in male and female rats.

Panfil K, Bailey C, Davis I, Mains A, Kirkpatrick K Behav Brain Res. 2019; 379:112316.

PMID: 31655096 PMC: 6917889. DOI: 10.1016/j.bbr.2019.112316.

Cognitive and behavioral training interventions to promote self-control.

Smith T, Panfil K, Bailey C, Kirkpatrick K J Exp Psychol Anim Learn Cogn. 2019; 45(3):259-279.

PMID: 31070430 PMC: 6716382. DOI: 10.1037/xan0000208.