Analysis of Fz10 Expression in Mouse Embryos

Overview

Journal Dev Genes Evol

Specialty Biology

Date 2004 Feb 6

PMID 14758554

Citations 12

Authors

Amy P Nunnally

Brian A Parr

Affiliations

Soon will be listed here.

Abstract

Wnt signaling molecules regulate the development of multiple organs in vertebrate embryos. We have isolated cDNA clones for frizzled10 (Fz10), which encodes a putative Wnt receptor, to further characterize the mechanisms of Wnt signaling in mouse embryos. Interestingly, Fz10 is expressed in the same regions as Wnt7a in the neural tube, limb buds, and Müllerian duct.

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References

Thomas K, Capecchi M . Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature. 1990; 346(6287):847-50. DOI: 10.1038/346847a0. View

Wodarz A, Nusse R . Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol. 1999; 14:59-88. DOI: 10.1146/annurev.cellbio.14.1.59. View

Stark K, Vainio S, Vassileva G, McMahon A . Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994; 372(6507):679-83. DOI: 10.1038/372679a0. View

Liu P, Wakamiya M, Shea M, Albrecht U, Behringer R, Bradley A . Requirement for Wnt3 in vertebrate axis formation. Nat Genet. 1999; 22(4):361-5. DOI: 10.1038/11932. View

Parr B, Shea M, Vassileva G, McMahon A . Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development. 1993; 119(1):247-61. DOI: 10.1242/dev.119.1.247. View

Pinson K, Brennan J, Monkley S, Avery B, Skarnes W . An LDL-receptor-related protein mediates Wnt signalling in mice. Nature. 2000; 407(6803):535-8. DOI: 10.1038/35035124. View

Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y . LDL-receptor-related proteins in Wnt signal transduction. Nature. 2000; 407(6803):530-5. DOI: 10.1038/35035117. View

Yang Y, Niswander L . Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell. 1995; 80(6):939-47. DOI: 10.1016/0092-8674(95)90297-x. View

Kawakami Y, Wada N, Nishimatsu S, Nohno T . Involvement of frizzled-10 in Wnt-7a signaling during chick limb development. Dev Growth Differ. 2001; 42(6):561-9. DOI: 10.1046/j.1440-169x.2000.00545.x. View

10.

Mao J, Wang J, Liu B, Pan W, Farr 3rd G, Flynn C . Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell. 2001; 7(4):801-9. DOI: 10.1016/s1097-2765(01)00224-6. View

11.

Wang Y, Macke J, Abella B, Andreasson K, Worley P, Gilbert D . A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996; 271(8):4468-76. DOI: 10.1074/jbc.271.8.4468. View

12.

McMahon A, Bradley A . The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 1990; 62(6):1073-85. DOI: 10.1016/0092-8674(90)90385-r. View

13.

Parr B, McMahon A . Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 1998; 395(6703):707-10. DOI: 10.1038/27221. View

14.

Frohman M, Dush M, Martin G . Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci U S A. 1988; 85(23):8998-9002. PMC: 282649. DOI: 10.1073/pnas.85.23.8998. View

15.

Hall A, LUCAS F, Salinas P . Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling. Cell. 2000; 100(5):525-35. DOI: 10.1016/s0092-8674(00)80689-3. View

16.

Miller C, Sassoon D . Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development. 1998; 125(16):3201-11. DOI: 10.1242/dev.125.16.3201. View

17.

Parr B, McMahon A . Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995; 374(6520):350-3. DOI: 10.1038/374350a0. View

18.

Vainio S, Heikkila M, Kispert A, Chin N, McMahon A . Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999; 397(6718):405-9. DOI: 10.1038/17068. View

19.

Kawakami Y, Wada N, Nishimatsu S, Komaguchi C, Noji S, Nohno T . Identification of chick frizzled-10 expressed in the developing limb and the central nervous system. Mech Dev. 2000; 91(1-2):375-8. DOI: 10.1016/s0925-4773(99)00301-9. View

20.

Bhanot P, Brink M, Samos C, Hsieh J, Wang Y, Macke J . A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature. 1996; 382(6588):225-30. DOI: 10.1038/382225a0. View