Second Primary Breast Cancer After Hodgkin's Disease

Overview

Journal Br J Cancer

Specialty Oncology

Date 2004 Jan 22

PMID 14735166

Citations 15

Authors

A Horwich

A J Swerdlow

Affiliations

Soon will be listed here.

Abstract

Although the potential carcinogenic risk of radiotherapy is well known, it has become clear that there is a particularly high risk of radiation-induced breast cancer in women treated for Hodgkin's disease at young ages. Thankfully, death from breast cancer in this population is uncommon, but it is important to understand factors contributing to the risk, including treatment parameters, and to develop a logical and efficient method for medical management of those at risk. In this minireview, we examine the evidence which should inform such a management policy.

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References

Hancock S, Tucker M, Hoppe R . Breast cancer after treatment of Hodgkin's disease. J Natl Cancer Inst. 1993; 85(1):25-31. DOI: 10.1093/jnci/85.1.25. View

Spaepen K, Stroobants S, Dupont P, Thomas J, Vandenberghe P, Balzarini J . Can positron emission tomography with [(18)F]-fluorodeoxyglucose after first-line treatment distinguish Hodgkin's disease patients who need additional therapy from others in whom additional therapy would mean avoidable toxicity?. Br J Haematol. 2001; 115(2):272-8. DOI: 10.1046/j.1365-2141.2001.03169.x. View

Biti G, Cimino G, Cartoni C, Magrini S, Anselmo A, Enrici R . Extended-field radiotherapy is superior to MOPP chemotherapy for the treatment of pathologic stage I-IIA Hodgkin's disease: eight-year update of an Italian prospective randomized study. J Clin Oncol. 1992; 10(3):378-82. DOI: 10.1200/JCO.1992.10.3.378. View

Aleman B, van den Belt-Dusebout A, Klokman W, Vant Veer M, Bartelink H, van Leeuwen F . Long-term cause-specific mortality of patients treated for Hodgkin's disease. J Clin Oncol. 2003; 21(18):3431-9. DOI: 10.1200/JCO.2003.07.131. View

Basu S, Schwartz C, Fisher S, Hudson M, Tarbell N, Muhs A . Unilateral and bilateral breast cancer in women surviving pediatric Hodgkin's disease. Int J Radiat Oncol Biol Phys. 2008; 72(1):34-40. PMC: 3532026. DOI: 10.1016/j.ijrobp.2008.04.068. View

Offit K, Gilad S, Paglin S, Kolachana P, Roisman L, Nafa K . Rare variants of ATM and risk for Hodgkin's disease and radiation-associated breast cancers. Clin Cancer Res. 2002; 8(12):3813-9. View

Rosenberg S, Kaplan H . The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962-1984. Int J Radiat Oncol Biol Phys. 1985; 11(1):5-22. DOI: 10.1016/0360-3016(85)90357-8. View

Tabar L, Yen M, Vitak B, Tony Chen H, Smith R, Duffy S . Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screening. Lancet. 2003; 361(9367):1405-10. DOI: 10.1016/S0140-6736(03)13143-1. View

Travis L, Hill D, Dores G, Gospodarowicz M, van Leeuwen F, Holowaty E . Breast cancer following radiotherapy and chemotherapy among young women with Hodgkin disease. JAMA. 2003; 290(4):465-75. DOI: 10.1001/jama.290.4.465. View

10.

Darby S, Reeves G, Key T, DOLL R, Stovall M . Mortality in a cohort of women given X-ray therapy for metropathia haemorrhagica. Int J Cancer. 1994; 56(6):793-801. DOI: 10.1002/ijc.2910560606. View

11.

Swerdlow A, Barber J, Hudson G, Cunningham D, Gupta R, Hancock B . Risk of second malignancy after Hodgkin's disease in a collaborative British cohort: the relation to age at treatment. J Clin Oncol. 2000; 18(3):498-509. DOI: 10.1200/JCO.2000.18.3.498. View

12.

Travis L, Curtis R, Boice Jr J . Late effects of treatment for childhood Hodgkin's disease. N Engl J Med. 1996; 335(5):352-3. View

13.

Yahalom J, Petrek J, Biddinger P, Kessler S, Dershaw D, McCormick B . Breast cancer in patients irradiated for Hodgkin's disease: a clinical and pathologic analysis of 45 events in 37 patients. J Clin Oncol. 1992; 10(11):1674-81. DOI: 10.1200/JCO.1992.10.11.1674. View

14.

Bhatia S, Robison L, Oberlin O, Greenberg M, Bunin G, Fossati-Bellani F . Breast cancer and other second neoplasms after childhood Hodgkin's disease. N Engl J Med. 1996; 334(12):745-51. DOI: 10.1056/NEJM199603213341201. View

15.

Bhatia S, Meadows A, Robison L . Family history of patients with breast cancer after treatment of Hodgkin's disease in childhood. Late Effects Study Group. Lancet. 1997; 350(9081):888-9. DOI: 10.1016/s0140-6736(05)62074-0. View

16.

Neglia J, Friedman D, Yasui Y, Mertens A, Hammond S, Stovall M . Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study. J Natl Cancer Inst. 2001; 93(8):618-29. DOI: 10.1093/jnci/93.8.618. View

17.

Tinger A, Wasserman T, Klein E, Miller E, Roberts T, Piephoff J . The incidence of breast cancer following mantle field radiation therapy as a function of dose and technique. Int J Radiat Oncol Biol Phys. 1997; 37(4):865-70. DOI: 10.1016/s0360-3016(97)00026-6. View

18.

van Leeuwen F, Klokman W, Veer M, Hagenbeek A, Krol A, Vetter U . Long-term risk of second malignancy in survivors of Hodgkin's disease treated during adolescence or young adulthood. J Clin Oncol. 2000; 18(3):487-97. DOI: 10.1200/JCO.2000.18.3.487. View

19.

Boice Jr J, Day N, Andersen A, Brinton L, Brown R, Choi N . Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries. J Natl Cancer Inst. 1985; 74(5):955-75. View

20.

Specht L, Gray R, Clarke M, Peto R . Influence of more extensive radiotherapy and adjuvant chemotherapy on long-term outcome of early-stage Hodgkin's disease: a meta-analysis of 23 randomized trials involving 3,888 patients. International Hodgkin's Disease Collaborative Group. J Clin Oncol. 1998; 16(3):830-43. DOI: 10.1200/JCO.1998.16.3.830. View