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Protein Import into Mitochondria: Two Systems Acting in Tandem?

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Specialty Cell Biology
Date 1991 Oct 1
PMID 14731796
Citations 24
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Abstract

Mitochondria can import proteins from the cytoplasm at sites where the two mitochondrial membranes are closely apposed. However, each of these membranes contains a distinct protein translocation channel. Recent evidence suggests that the two types of channel are not permanently coupled, but may dissociate in a reversible manner. This reversible interaction is probably essential for intramitochondrial sorting proteins.

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