Hepatic Fibrosis and Survival in Biliary Atresia

Overview

Journal J Pediatr

Specialty Pediatrics

Date 2004 Jan 15

PMID 14722530

Citations 46

Authors

Viraine S Weerasooriya

Frances V White

Ross W Shepherd

Affiliations

Soon will be listed here.

Abstract

In biliary atresia, progression of hepatic fibrosis before the Kasai portoenterostomy may explain why age is a major determinant of survival of the native liver. Blinded fibrosis scoring of surgical liver biopsies demonstrated that age and fibrosis correlate. Those biopsies with severe fibrosis predicted significantly worse survival.

Citing Articles

Impact of follow-up liver biopsy on long-term outcomes post-Kasai procedure in patients with biliary atresia.

Takase K, Ueno T, Matsumoto S, Uga N, Deguchi K, Nomura M Pediatr Surg Int. 2025; 41(1):88.

PMID: 40019581 PMC: 11870969. DOI: 10.1007/s00383-025-05979-y.

Modified Kasai operation combined with autologous bone marrow mononuclear cell infusion for biliary atresia.

Thanh L, Nguyen H, Kieu T, Duy M, Ha H, Thi H BMC Surg. 2024; 24(1):368.

PMID: 39568009 PMC: 11577823. DOI: 10.1186/s12893-024-02669-9.

Amyloid precursor protein as a fibrosis marker in infants with biliary atresia.

Kamp J, Madadi-Sanjani O, Uecker M, Werlein C, Neubert L, Kubler J Pediatr Res. 2024; .

PMID: 39341941 DOI: 10.1038/s41390-024-03582-w.

Development and post-Kasai procedure prognostic relevance of histological features for biliary atresia.

Xu X, Wang X, Ding M, Zhao Y, Zhao L, Zhao L BMC Pediatr. 2023; 23(1):589.

PMID: 37993876 PMC: 10664255. DOI: 10.1186/s12887-023-04413-3.

Performance of two-dimensional shear wave elastography for detecting advanced liver fibrosis and cirrhosis in patients with biliary atresia: a systematic review and meta-analysis.

Dong B, Duan Y, Wang H, Chen Y, Lyu G Pediatr Radiol. 2023; 53(13):2642-2650.

PMID: 37917168 DOI: 10.1007/s00247-023-05796-2.