Quinolone Resistance Among Escherichia Coli Strains from Community-acquired Urinary Tract Infections in Greece

Overview

Journal Clin Microbiol Infect

Publisher Elsevier

Specialty Infectious Diseases

Date 2004 Jan 7

PMID 14706091

Citations 16

Authors

S Chaniotaki

P Giakouppi

L S Tzouvelekis

D Panagiotakos

M Kozanitou

G Petrikkos

A Avlami

A C Vatopoulos

Affiliations

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Abstract

Susceptibility data for 10 049 Escherichia coli isolates derived from community-acquired urinary tract infections in Greece during the period January 2000 to June 2002 indicated 8.1% resistance to nalidixic acid and 36% resistance to ciprofloxacin. In a sample of 170 E. coli isolates, mutations in gyrA (25 isolates) and parC (15 isolates) were consistent with the levels of resistance to quinolones. Previous exposure to quinolones and underlying chronic disease were independent risk factors for infection by quinolone-resistant E. coli strains.

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