Analysis of the Requirement for Glycoprotein M in Herpes Simplex Virus Type 1 Morphogenesis

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2003 Dec 25

PMID 14694137

Citations 28

Authors

Helena Browne

Susanne Bell

Tony Minson

Affiliations

Soon will be listed here.

Abstract

A mutant of herpes simplex virus type 1 lacking both glycoprotein M and glycoprotein E was marginally compromised in terms of its in vitro growth characteristics. This finding is in marked contrast to a similar mutant of the related alphaherpesvirus, pseudorabies virus (A. R. Brack, J. M. Dijkstra, H. Granzow, B. G. Klupp, and T. C. Mettenleiter, J. Virol. 73:5364-5372, 1999), and suggests that the glycoprotein requirements for virion assembly may vary among different members of this family of viruses.

Citing Articles

glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology.

Ning Y, Huang Y, Wang M, Cheng A, Yang Q, Wu Y Front Microbiol. 2022; 13:970545.

PMID: 35992696 PMC: 9386159. DOI: 10.3389/fmicb.2022.970545.

Herpesvirus Nuclear Egress across the Outer Nuclear Membrane.

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The Roles of Envelope Glycoprotein M in the Life Cycle of Some Alphaherpesviruses.

Li C, Wang M, Cheng A, Jia R, Yang Q, Wu Y Front Microbiol. 2021; 12:631523.

PMID: 33679658 PMC: 7933518. DOI: 10.3389/fmicb.2021.631523.

Characterization of the Herpes Simplex Virus (HSV) Tegument Proteins That Bind to gE/gI and US9, Which Promote Assembly of HSV and Transport into Neuronal Axons.

DuRaine G, Wisner T, Johnson D J Virol. 2020; 94(23).

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HSV-1 Cytoplasmic Envelopment and Egress.

Ahmad I, Wilson D Int J Mol Sci. 2020; 21(17).

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