Evaluating Glutamatergic Transmission in Schizophrenia

Overview

Journal Ann N Y Acad Sci

Specialty Science

Date 2003 Dec 20

PMID 14684439

Citations 14

Authors

Carol A Tamminga

Adrienne C Lahti

Deborah R Medoff

Xue-Min Gao

Henry H Holcomb

Affiliations

Soon will be listed here.

Abstract

Our findings with schizophrenia and the glutamate system have relied on the characterization of the clinical response of patients to ketamine and their functional brain imaging response (rCBF) to the drug. Prior to the human studies reported here, we had evaluated the region activation characteristics and pharmacology of PCP and its congener MK 801 in animals. What I will report in this paper has been individually reported elsewhere but brought together here in a new synthesis.

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