Postcolumn HPLC Detection of Mono- and Oligosaccharides with a Chemosensor

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2003 Dec 20

PMID 14682751

Citations 11

Authors

Kyu Kwang Kim

Jorge O Escobedo

Nadia N St Luce

Oleksandr Rusin

Douglas Wong

Robert M Strongin

Affiliations

Soon will be listed here.

Abstract

Novel chromophoric compound 1 promotes the HPLC postcolumn detection of mono- and oligosaccharides. The detection of chromatographic peaks in the visible region for glucose, fructose, maltodextrins, sialic acid, and a ganglioside can be accomplished with a standard UV-vis detector. The use of selective, reversible binding agents in automated HPLC assays should allow for improved monitoring of specific analytes as well as material recovery. [structure: see text]

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