Chemical Contaminants and Their Effects in Fish and Wildlife from the Industrial Zone of Sumgayit, Republic of Azerbaijan

Overview

Journal Ecotoxicology

Specialties Environmental Health
Toxicology

Date 2003 Dec 19

PMID 14680332

Citations 9

Authors

Carol D Swartz

K C Donnelly

Arif Islamzadeh

Gilbert T Rowe

William J Rogers

Grigoriy M Palatnikov

Arif A Mekhtiev

Rafik Kasimov

Thomas J McDonald

Jeffery K Wickliffe

Bobby J Presley

John W Bickham

Affiliations

Soon will be listed here.

Abstract

Sediment from a wetland adjacent to an industrial wastewater treatment plant in Sumgayit contained concentrations of total PAHs, total PCBs, aldrin, biphenyl, chlordane, DDT, mercury, beta-endosulfan, heptachlor, alpha-hexacyclohexane (alpha-HCH), gamma-HCH, and several individual PAH congeners that were elevated relative to published sediment quality guidelines. Chemical analyses of tissues from European pond turtles (Emys orbicularis) had increased levels of many of the same chemicals including aldrin, chlordane, heptachlor, alpha-HCH, total PCBs, total PAHs, and mercury, compared to reference turtles. In addition, turtle tissues contained elevated levels of DDD, hexachlorobenzene (HCB), and pentachlorobenzene that were not elevated in the sediment sample. Some differences were observed in contaminant levels between European pond turtles and Caspian turtles (Mauremys caspica) taken from the ponds in Sumgayit. Salmonella/microsome mutagenicity assays on pond sediments were negative or weakly positive. Micronuclei in European pond turtles were statistically correlated with tissue levels of mercury, heptachlor, DDD, HCB, and trans-nonachlor. Microcosm experiments using Russian sturgeon (Acipenser gueldenstaedtii) showed a positive dose-response relationship between exposure to suspended contaminated pond sediment and acute toxicity. Chemical and biological assays used in this study show the industrial area of Sumgayit is heavily contaminated with a complex mixture of toxic pollutants. Exposure to contaminated sediments produced acute effects in Russian sturgeon, but genotoxic effects appear to be slight.

Citing Articles

Toxic Site Identification Program in Azerbaijan.

Abbasov R, Cervantes de Blois C, Sharov P, Temnikova A, Karimov R, Karimova G Environ Manage. 2019; 64(6):794-808.

PMID: 31748949 DOI: 10.1007/s00267-019-01215-1.

Influence of organic carbon and metal oxide phases on sorption of 2,4,6-trichlorobenzoic acid under oxic and anoxic conditions.

Ololade I, Oladoja N, Alomaja F, Ololade O, Olaseni E, Oloye F Environ Monit Assess. 2014; 187(1):4170.

PMID: 25433543 DOI: 10.1007/s10661-014-4170-2.

The legacy of persistent organic pollutants in Azerbaijan: an assessment of past use and current contamination.

Aliyeva G, Halsall C, Alasgarova K, Avazova M, Ibrahimov Y, Aghayeva R Environ Sci Pollut Res Int. 2012; 20(4):1993-2008.

PMID: 22825638 DOI: 10.1007/s11356-012-1076-9.

Organochlorine pesticides and polychlorinated biphenyls in air and soil across Azerbaijan.

Aliyeva G, Kurkova R, Hovorkova I, Klanova J, Halsall C Environ Sci Pollut Res Int. 2012; 19(6):1953-62.

PMID: 22767293 DOI: 10.1007/s11356-012-0944-7.

Evolutionary toxicology: contaminant-induced genetic mutations in mosquitofish from Sumgayit, Azerbaijan.

Rinner B, Matson C, Islamzadeh A, McDonald T, Donnelly K, Bickham J Ecotoxicology. 2011; 20(2):365-76.

PMID: 21312027 DOI: 10.1007/s10646-010-0587-8.

References

Dickerson R, Hooper M, Gard N, Cobb G, Kendall R . Toxicological foundations of ecological risk assessment: biomarker development and interpretation based on laboratory and wildlife species. Environ Health Perspect. 1994; 102 Suppl 12:65-9. PMC: 1566735. DOI: 10.1289/ehp.94102s1265a. View

Custer T, Custer C, Hines R, Sparks D, Melancon M, Hoffman D . Mixed-function oxygenases, oxidative stress, and chromosomal damage measured in lesser scaup wintering on the Indiana Harbor Canal. Arch Environ Contam Toxicol. 2000; 38(4):522-9. DOI: 10.1007/s002449910068. View

Lamb T, Bickham J, Lyne T, Gibbons J . The slider turtle as an environmental sentinel: multiple tissue assays using flow cytometric analysis. Ecotoxicology. 2013; 4(1):5-13. DOI: 10.1007/BF00350647. View

Venkat J, Shami S, Davis K, Nayak M, Plimmer J, Pfeil R . Relative genotoxic activities of pesticides evaluated by a modified SOS microplate assay. Environ Mol Mutagen. 1995; 25(1):67-76. DOI: 10.1002/em.2850250110. View

Schoeny R . Use of genetic toxicology data in U.S. EPA risk assessment: the mercury study report as an example. Environ Health Perspect. 1996; 104 Suppl 3:663-73. PMC: 1469637. DOI: 10.1289/ehp.96104s3663. View

Guttman S . Population genetic structure and ecotoxicology. Environ Health Perspect. 1994; 102 Suppl 12:97-100. PMC: 1566725. DOI: 10.1289/ehp.94102s1297. View

Bickham J, Rowe G, Palatnikov G, Mekhtiev A, Mekhtiev M, Kasimov R . Acute and genotoxic effects of Baku Harbor sediment on Russian sturgeon, Acipenser guildensteidti. Bull Environ Contam Toxicol. 1998; 61(4):512-8. DOI: 10.1007/s001289900792. View

Moriya M, Ohta T, Watanabe K, Miyazawa T, Kato K, Shirasu Y . Further mutagenicity studies on pesticides in bacterial reversion assay systems. Mutat Res. 1983; 116(3-4):185-216. DOI: 10.1016/0165-1218(83)90059-9. View

Bickham J, Sandhu S, Hebert P, Chikhi L, Athwal R . Effects of chemical contaminants on genetic diversity in natural populations: implications for biomonitoring and ecotoxicology. Mutat Res. 2000; 463(1):33-51. DOI: 10.1016/s1383-5742(00)00004-1. View

10.

Ames B, McCann J, Yamasaki E . Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat Res. 1975; 31(6):347-64. DOI: 10.1016/0165-1161(75)90046-1. View

11.

Shelby M . The genetic toxicity of human carcinogens and its implications. Mutat Res. 1988; 204(1):3-15. DOI: 10.1016/0165-1218(88)90113-9. View

12.

Hooper M, La Point T . Contaminant effects in the environment: their use in waste site assessment. Cent Eur J Public Health. 1994; 2 Suppl:65-9. View

13.

Ashby J, Tennant R . Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP. Mutat Res. 1988; 204(1):17-115. DOI: 10.1016/0165-1218(88)90114-0. View

14.

Tennant R, Margolin B, Shelby M, Zeiger E, Haseman J, Spalding J . Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays. Science. 1987; 236(4804):933-41. DOI: 10.1126/science.3554512. View

15.

Heddle J, Hite M, Kirkhart B, Mavournin K, MacGregor J, NEWELL G . The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res. 1983; 123(1):61-118. DOI: 10.1016/0165-1110(83)90047-7. View

16.

Sericano J, Brooks J, Champ M, Kennicutt 2nd M, Makeyev V . Trace contaminant concentrations in the Kara Sea and its adjacent rivers, Russia. Mar Pollut Bull. 2002; 42(11):1017-30. DOI: 10.1016/s0025-326x(00)00236-8. View

17.

Chu K, Patel K, Lin A, Tarone R, Linhart M, Dunkel V . Evaluating statistical analyses and reproducibility of microbial mutagenicity assays. Mutat Res. 1981; 85(3):119-32. DOI: 10.1016/0165-1161(81)90027-3. View

18.

MARON D, Ames B . Revised methods for the Salmonella mutagenicity test. Mutat Res. 1983; 113(3-4):173-215. DOI: 10.1016/0165-1161(83)90010-9. View

19.

Anderson S, Sadinski W, Shugart L, Brussard P, Depledge M, Ford T . Genetic and molecular ecotoxicology: a research framework. Environ Health Perspect. 1994; 102 Suppl 12:3-8. PMC: 1566742. DOI: 10.1289/ehp.94102s123. View

20.

Kier L, Brusick D, Auletta A, Von Halle E, Brown M, Simmon V . The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res. 1986; 168(2):69-240. DOI: 10.1016/0165-1110(86)90002-3. View