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Transcriptome Analysis of the Response of Pseudomonas Aeruginosa to Hydrogen Peroxide

Overview
Journal J Bacteriol
Specialty Microbiology
Date 2003 Dec 18
PMID 14679246
Citations 86
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Abstract

Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H(2)O(2) and untreated controls. The data indicate that the early response of P. aeruginosa to H(2)O(2) consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.

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