Postnatal Development of the Basolateral Complex of Rabbit Amygdala: a Stereological and Histochemical Study

Overview

Journal J Anat

Specialty Anatomy & Histology

Date 2003 Nov 26

PMID 14635804

Citations 8

Authors

H Jagalska-Majewska

S Wojcik

J Dziewiatkowski

A Luczynska

R Kurlapska

J Morys

Affiliations

Soon will be listed here.

Abstract

The aim of the study was to estimate developmental changes in the rabbit basolateral complex (BLC) by stereological and histochemical methods. Material consisted of 45 brains of New Zealand rabbits (aged from 2 to 180 days, P2 to P180) of both sexes, divided into nine groups. The following parameters were estimated: volume of the cerebral hemisphere; volume of the whole BLC and of particular BLC nuclei; neuronal density and total number of neurons in these nuclei. Developmental changes in acetylcholinesterase (AChE) activity in the BLC were also examined. The volume of the cerebral hemisphere increased until P30, whereas volumes of nuclei increased for longer--until P90. The density of neurons in all nuclei studied reached the level characteristic for an adult animal at about P30. The total number of neurons in the dorsolateral division of the lateral nucleus (Ldl) stabilized the earliest--between P30 and P60, whereas in the ventromedial division of the lateral nucleus (Lvm), basomedial (BM) and basolateral (BL) nuclei the number stabilized later--between P60 and P90. AChE activity appears minimal in the BLC on P2, reaches a maximum on P30 and then decreases to the level characteristic of an adult animal on P60. AChE activity was greater in BL than in other nuclei in all age groups. Reaching adult AChE activity 1 month earlier than the total number of neurons in the BLC may indicate a role of the cholinergic system in BLC maturation.

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References

Bayer S, Yackel J, Puri P . Neurons in the rat dentate gyrus granular layer substantially increase during juvenile and adult life. Science. 1982; 216(4548):890-2. DOI: 10.1126/science.7079742. View

Bayer S . Changes in the total number of dentate granule cells in juvenile and adult rats: a correlated volumetric and 3H-thymidine autoradiographic study. Exp Brain Res. 1982; 46(3):315-23. DOI: 10.1007/BF00238626. View

Kostovic I, Goldman-Rakic P . Transient cholinesterase staining in the mediodorsal nucleus of the thalamus and its connections in the developing human and monkey brain. J Comp Neurol. 1983; 219(4):431-47. DOI: 10.1002/cne.902190405. View

Sterio D . The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc. 1984; 134(Pt 2):127-36. DOI: 10.1111/j.1365-2818.1984.tb02501.x. View

Kapp B, Schwaber J, Driscoll P . Frontal cortex projections to the amygdaloid central nucleus in the rabbit. Neuroscience. 1985; 15(2):327-46. DOI: 10.1016/0306-4522(85)90216-7. View

Gundersen H . Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J Microsc. 1986; 143(Pt 1):3-45. View

Robertson R . A morphogenic role for transiently expressed acetylcholinesterase in developing thalamocortical systems?. Neurosci Lett. 1987; 75(3):259-64. DOI: 10.1016/0304-3940(87)90531-3. View

Last A, Greenfield S . Acetylcholinesterase has a non-cholinergic neuromodulatory action in the guinea-pig substantia nigra. Exp Brain Res. 1987; 67(2):445-8. DOI: 10.1007/BF00248567. View

Anderson R, Key B . Role of acetylcholinesterase in the development of axon tracts within the embryonic vertebrate brain. Int J Dev Neurosci. 1999; 17(8):787-93. DOI: 10.1016/s0736-5748(99)00064-7. View

10.

Bennett-Clarke C, Chiaia N, Rhoades R . Differential expression of acetylcholinesterase in the brainstem, ventrobasal thalamus and primary somatosensory cortex of perinatal rats, mice, and hamsters. Somatosens Mot Res. 2000; 16(4):269-79. DOI: 10.1080/08990229970339. View

11.

Nissinen J, Halonen T, Koivisto E, Pitkanen A . A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat. Epilepsy Res. 2000; 38(2-3):177-205. DOI: 10.1016/s0920-1211(99)00088-1. View

12.

Hariri A, Bookheimer S, Mazziotta J . Modulating emotional responses: effects of a neocortical network on the limbic system. Neuroreport. 2000; 11(1):43-8. DOI: 10.1097/00001756-200001170-00009. View

13.

Pitkanen A, Jolkkonen E, Kemppainen S . Anatomic heterogeneity of the rat amygdaloid complex. Folia Morphol (Warsz). 2000; 59(1):1-23. View

14.

Lev-Lehman E, Evron T, Broide R, Meshorer E, Ariel I, Seidman S . Synaptogenesis and myopathy under acetylcholinesterase overexpression. J Mol Neurosci. 2000; 14(1-2):93-105. DOI: 10.1385/JMN:14:1-2:093. View

15.

Morys J, Berdel B, Jagalska-Majewska H, Luczynska A . The basolateral amygdaloid complex--its development, morphology and functions. Folia Morphol (Warsz). 2000; 58(3 Suppl 2):29-46. View

16.

Morrison A, Sanford L, Ross R . The amygdala: a critical modulator of sensory influence on sleep. Biol Signals Recept. 2000; 9(6):283-96. DOI: 10.1159/000014652. View

17.

Gundersen H, Jensen E . The efficiency of systematic sampling in stereology and its prediction. J Microsc. 1987; 147(Pt 3):229-63. DOI: 10.1111/j.1365-2818.1987.tb02837.x. View

18.

Greenfield S, Jack J, Last A, French M . An electrophysiological action of acetylcholinesterase independent of its catalytic site. Exp Brain Res. 1988; 70(2):441-4. DOI: 10.1007/BF00248370. View

19.

Chateau D, Aron C . Heterotypic sexual behavior in male rats after lesions in different amygdaloid nuclei. Horm Behav. 1988; 22(3):379-87. DOI: 10.1016/0018-506x(88)90009-8. View

20.

Kristt D . Acetylcholinesterase in immature thalamic neurons: relation to afferentation, development, regulation and cellular distribution. Neuroscience. 1989; 29(1):27-43. DOI: 10.1016/0306-4522(89)90330-8. View