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Validity of Performance Indicators for Assessing Prescribing Quality: the Case of Asthma

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Specialty Pharmacology
Date 2003 Nov 19
PMID 14624323
Citations 10
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Abstract

Objectives: The aim of this study was to assess the concurrent validity between the identification of sub-optimal treatment based on clinical information and computer generated indicators. Indicators that are associated with sub-optimal treatment in one of the four steps of asthma management were assessed.

Design: The ability of each indicator to identify patients with sub-optimal asthma treatment from computerised general practitioner (GP) prescription records was assessed by comparing them with the results of an individual patient assessment using clinical data.

Setting: Chronic asthma patients ( n=146) registered with 16 Dutch GPs.

Main Measures: The sensitivity and positive predictive value (PPV) of each performance indicator was determined.

Results: The step-1 indicator, focusing on patients not prescribed a short-acting beta-agonist, had an acceptable sensitivity (0.86), but a low PPV (0.52). The two step-2 indicators, targeting under-prescription of inhaled corticosteroids, had sensitivities of 0.74 and 0.37 and PPVs of 0.46 and 0.71, respectively. The step-3 indicator, which targeted under-dosing of inhaled corticosteroids, had a sensitivity of 0.07 and a PPV of 0.2. The fourth indicator, focusing on under-prescription of long-acting beta-agonists, could not be validated due to inadequate numbers of patients with severe asthma in our study sample.

Discussion: None of the indicators investigated was considered valid for assessing prescriber performance, despite having good face and content validity. Performance indicators that have not been validated can only provide a broad-brush approach for assessing prescribing quality and should be used with extreme caution.

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References
1.
Poloniecki J . Half of all doctors are below average. BMJ. 1998; 316(7146):1734-6. PMC: 1113280. DOI: 10.1136/bmj.316.7146.1734. View

2.
Hallas J, Hansen N . Individual utilization of anti-asthma medication by young adults: a prescription database analysis. J Intern Med. 1993; 234(1):65-70. DOI: 10.1111/j.1365-2796.1993.tb00706.x. View

3.
Lagerlov P, Loeb M, Andrew M, Hjortdahl P . Improving doctors' prescribing behaviour through reflection on guidelines and prescription feedback: a randomised controlled study. Qual Health Care. 2000; 9(3):159-65. PMC: 1743532. DOI: 10.1136/qhc.9.3.159. View

4.
Wahlstrom R, Lagerlov P, Lundborg C, Veninga CCM , Hummers-Pradier E, Dahlgren L . Variations in general practitioners' views of asthma management in four European countries. Soc Sci Med. 2001; 53(4):507-18. DOI: 10.1016/s0277-9536(00)00356-7. View

5.
West S, Savitz D, Koch G, Strom B, Guess H, Hartzema A . Recall accuracy for prescription medications: self-report compared with database information. Am J Epidemiol. 1995; 142(10):1103-12. DOI: 10.1093/oxfordjournals.aje.a117563. View