Pathogenesis of Murine Cytomegalovirus Infection

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2003 Nov 19

PMID 14623023

Citations 126

Authors

Astrid Krmpotic

Ivan Bubic

Bojan Polic

Pero Lucin

Stipan Jonjic

Affiliations

Soon will be listed here.

Abstract

Infection of mice with murine cytomegalovirus (MCMV) is an established model for studying human cytomegalovirus (HCMV) infection. Similarly to HCMV infection, pathological changes and disease manifestations during MCMV infection are mainly dependent on the immune status of the mouse host. This review focuses mainly on the pathogenesis of MCMV infection in immunocompetent and immunodeficient and/or immature mice and discusses the principles of immunosurveillance of infection and the mechanisms by which this virus evades immune control.

Citing Articles

Susceptibility of Mouse Brain to MCMV Infection and Neuroinflammation During Ontogeny.

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The Multifaceted Roles of NK Cells in the Context of Murine Cytomegalovirus and Lymphocytic Choriomeningitis Virus Infections.

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Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells.

Ebert S, Bohm V, Buttner J, Brune W, Brinkmann M, Holtappels R PLoS Pathog. 2024; 20(8):e1012173.

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Murine Models of Secondary Cytokine Storm Syndromes.

Brisse E, Verweyen E, De Visscher A, Kessel C, Wouters C, Matthys P Adv Exp Med Biol. 2024; 1448:497-522.

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