» Articles » PMID: 14606061

Gut in Diseases: Physiological Elements and Their Clinical Significance

Overview
Specialty Gastroenterology
Date 2003 Nov 8
PMID 14606061
Citations 12
Authors
Affiliations
Soon will be listed here.
Abstract

The intestinal barrier function of GI tract is very important in the body except for the function of digestion and absorption. The functional status of gut barrier basically reflects the stress severity when body suffers from trauma and various stimulations. Many harmful factors such as drugs, illnesses, trauma and burns can damage the gut barrier, which can lead to the barrier dysfunction and bacterial/endotoxin translocation. The paper discusses and reviews the concepts, anatomy, pathophysiology of gut barrier and its clinical relations.

Citing Articles

Molecular Mechanisms of , LGG Probiotic Function.

Leser T, Baker A Microorganisms. 2024; 12(4).

PMID: 38674738 PMC: 11051730. DOI: 10.3390/microorganisms12040794.


Intestinal melatonin levels and gut microbiota homeostasis are independent of the pineal gland in pigs.

Zheng J, Zhou Y, Zhang D, Ma K, Gong Y, Luo X Front Microbiol. 2024; 15:1352586.

PMID: 38596375 PMC: 11003461. DOI: 10.3389/fmicb.2024.1352586.


Influence of Different Light Spectra on Melatonin Synthesis by the Pineal Gland and Influence on the Immune System in Chickens.

Horodincu L, Solcan C Animals (Basel). 2023; 13(13).

PMID: 37443893 PMC: 10340020. DOI: 10.3390/ani13132095.


Necrotizing pancreatitis complicated by retroperitoneal emphysema: two case reports.

Chida K, Ishido K, Sakamoto Y, Kimura N, Morohashi H, Miura T Surg Case Rep. 2022; 8(1):183.

PMID: 36163599 PMC: 9512950. DOI: 10.1186/s40792-022-01542-2.


Microbiome analysis reveals that Ralstonia is responsible for decreased renal function in patients with ulcerative colitis.

Kim J, Rim J, Kim D, Kim H, Choi S, Kim D Clin Transl Med. 2021; 11(3):e322.

PMID: 33784015 PMC: 7933010. DOI: 10.1002/ctm2.322.


References
1.
Nadler E, Ford H . Regulation of bacterial translocation by nitric oxide. Pediatr Surg Int. 2000; 16(3):165-8. DOI: 10.1007/s003830050714. View

2.
Zhou X, Li Y, Li N, Li J . Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment. World J Gastroenterol. 2002; 7(1):66-73. PMC: 4688703. DOI: 10.3748/wjg.v7.i1.66. View

3.
van der Hulst R, Von Meyenfeldt M, van Kreel B, Thunnissen F, Brummer R, Arends J . Gut permeability, intestinal morphology, and nutritional depletion. Nutrition. 1998; 14(1):1-6. DOI: 10.1016/s0899-9007(97)00385-7. View

4.
Allison M, Howatson A, Torrance C, Lee F, Russell R . Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs. N Engl J Med. 1992; 327(11):749-54. DOI: 10.1056/NEJM199209103271101. View

5.
OBoyle C, MacFie J, Dave K, Sagar P, Poon P, Mitchell C . Alterations in intestinal barrier function do not predispose to translocation of enteric bacteria in gastroenterologic patients. Nutrition. 1998; 14(4):358-62. DOI: 10.1016/s0899-9007(97)00488-7. View