Volumetric Diffuse Optical Tomography of Brain Activity

Overview

Journal Opt Lett

Specialty Ophthalmology

Date 2003 Nov 1

PMID 14587815

Citations 50

Authors

Joseph P Culver

Andrew M Siegel

Jonathan J Stott

David A Boas

Affiliations

Soon will be listed here.

Abstract

We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.

Citing Articles

Rapid diffused optical imaging for accurate 3D estimation of subcutaneous tissue features.

Cai S, Mai J, Hong W, Fraser S, Cutrale F iScience. 2025; 28(2):111818.

PMID: 39991548 PMC: 11847144. DOI: 10.1016/j.isci.2025.111818.

Diffuse optical tomography of the brain: effects of inaccurate baseline optical parameters and refinements using learned post-processing.

Mozumder M, Hirvi P, Nissila I, Hauptmann A, Ripoll J, Singh D Biomed Opt Express. 2024; 15(8):4470-4485.

PMID: 39347006 PMC: 11427210. DOI: 10.1364/BOE.524245.

Network organization of resting-state cerebral hemodynamics and their aliasing contributions measured by functional near-infrared spectroscopy.

Zhang F, Khan A, Ding L, Yuan H J Neural Eng. 2022; 20(1).

PMID: 36535032 PMC: 9855663. DOI: 10.1088/1741-2552/acaccb.

Adaptive Feature Extraction for Blood Vessel Segmentation and Contrast Recalculation in Laser Speckle Contrast Imaging.

Morales-Vargas E, Padilla-Martinez J, Peregrina-Barreto H, Garcia-Suastegui W, Ramirez-San-Juan J Micromachines (Basel). 2022; 13(10).

PMID: 36296143 PMC: 9609016. DOI: 10.3390/mi13101788.

Fu X, Richards J J Biomed Opt. 2022; 27(8).

PMID: 35810323 PMC: 9270691. DOI: 10.1117/1.JBO.27.8.083004.