Diagnostic and Prognostic Prediction Using Gene Expression Profiles in High-dimensional Microarray Data

Overview

Journal Br J Cancer

Specialty Oncology

Date 2003 Oct 30

PMID 14583755

Citations 43

Authors

R Simon

Affiliations

Soon will be listed here.

Abstract

DNA microarrays are a potentially powerful technology for improving diagnostic classification, treatment selection and therapeutics development. There are, however, many potential pitfalls in the use of microarrays that result in false leads and erroneous conclusions. This paper provides a review of the key features to be observed in developing diagnostic and prognostic classification systems based on gene expression profiling and some of the pitfalls to be aware of in reading reports of microarray-based studies.

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