Increased Density of Human Immunodeficiency Virus Type 1 Coreceptors CCR5 and CXCR4 on the Surfaces of CD4(+) T Cells and Monocytes of Patients with Schistosoma Mansoni Infection

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 2003 Oct 24

PMID 14573694

Citations 43

Authors

W Evan Secor

Amil Shah

Pauline M N Mwinzi

Bryson A Ndenga

Caroline O Watta

Diana M S Karanja

Affiliations

Soon will be listed here.

Abstract

Distribution of chemokine receptors CCR5 and CXCR4, which are also coreceptors for human immunodeficiency virus type 1 invasion of cells, was measured on the surfaces of CD4(+) T cells and monocytes in peripheral blood samples from a group of Kenyan car washers. Patients with active schistosomiasis displayed higher cell surface densities of these receptors than did cured schistosomiasis patients.

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