Tumor Escape from Immune Response: Mechanisms and Targets of Activity

Overview

Journal Curr Drug Targets

Publisher Bentham Science Publishers

Specialty Pharmacology

Date 2003 Oct 11

PMID 14535653

Citations 31

Authors

Dmitry Gabrilovich

Vladimir Pisarev

Affiliations

Soon will be listed here.

Abstract

Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.

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