» Articles » PMID: 1452093

The Possibilities of Changing the Production of Exocellular Polysaccharides of a Mutant Mycobacterium Strain

Overview
Publisher Springer
Specialty Microbiology
Date 1992 Jan 1
PMID 1452093
Authors
Affiliations
Soon will be listed here.
Abstract

By second-step mutagenesis and treatment with N-methyl-N'-nitro-N-nitrosoguanidine a mutant strain of Mycobacterium sp. V-649 producing a glucan extracellular polymer and another new streptomycin-resistant mutant were prepared. This mutant strain formed more than 100% first-rate (1.0-1.2%) exocellular polysaccharide. Treatment with 1% dimethyl sulfoxide during submerged cultivation of the mutant strain did not increase the production of the extracellular polysaccharide.

References
1.
Gogoleva E, Grechuskina N, Egorov N, BIRIUZOVA V . [Polysaccharides of free slime, capsule and cell wall of Mycobacterium lacticolum]. Mikrobiologiia. 1976; 45(6):984-6. View

2.
Botvinko I, GRECHUSHKINA N, Gladko I, Egorov N . [Conditions for exopolysaccharide biosynthesis by Mycobacterium mucosum and its composition]. Mikrobiologiia. 1981; 50(2):229-33. View

3.
KONICEK J, Malek I . The use of nitrosoguanidine in the study of mutagenesis in a non-acid-fast strain of Mycobacterium phlei. Folia Microbiol (Praha). 1970; 15(2):82-7. DOI: 10.1007/BF02880089. View

4.
KONICEK J, Smekal F . Effect of Tween 80 and dimethyl sulfoxide on biosynthesis of L-lysine in regulatory mutants of Corynebacterium glutamicum. Folia Microbiol (Praha). 1991; 36(6):587-9. DOI: 10.1007/BF02884043. View

5.
Malek I . The mutagenic effect of nitrosoguanidine on Mycobacterium phlei PA. Folia Microbiol (Praha). 1969; 14(3):201-7. DOI: 10.1007/BF02872779. View