Titin: Properties and Family Relationships

Overview

Journal Nat Rev Mol Cell Biol

Specialties Cell Biology
Molecular Biology

Date 2003 Sep 25

PMID 14506471

Citations 128

Authors

Larissa Tskhovrebova

John Trinick

Affiliations

Soon will be listed here.

Abstract

In striated muscles, the rapid production of macroscopic levels of force and displacement stems directly from highly ordered and hierarchical protein organization, with the sarcomere as the elemental contractile unit. There is now a wealth of evidence indicating that the giant elastic protein titin has important roles in controlling the structure and extensibility of vertebrate muscle sarcomeres.

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