Ultrastructural and Immunocytochemical Study of a Primary Gastrinoma of the Liver

Overview

Journal Ultrastruct Pathol

Publisher Informa Healthcare

Date 1992 Nov 1

PMID 1448886

Citations 7

Authors

J Larriva-Sahd

A Angeles-Angeles

R Hernandez-Pando

L Munoz Fernandez

A Rondan

H Orozco Estevez

M Campuzano Fernandez

Affiliations

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Abstract

A primary hepatic gastrinoma found in a 13-year-old boy was studied by light microscopy, immunohistochemistry, electron microscopy, and immunoelectron microscopy. Results were consistent with a neuroendocrine neoplasm with abundant gastrin-immunoreactive cells. Unlike all previously reported cases of primary hepatic neuroendocrine tumors, which have been endocrinologically asymptomatic, the patient had a Zollinger-Ellison syndrome apparently cured by surgical resection of the tumor.

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[Primary neuroendocrine carcinoma of the liver. From carcinoid tumor to small-cell hepatic carcinoma: case reports and review of the literature].

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