A Simple Method for the Determination of Serum Haptoglobins

Overview

Journal J Clin Pathol

Specialty Pathology

Date 1960 Mar 1

PMID 14429549

Citations 28

Authors

J A Owen

F C BETTER

J Hoban

Affiliations

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Abstract

Changes in the serum haptoglobin level have been reported in certain forms of anaemia (Allison and ap Rees, 1957; Allison, 1958; Nosslin and Nyman, 1958; Nyman, Gydell, and Nosslin, 1959), in hepatobiliary disease (Owen, Mackay, and Got, 1959) and in various inflammatory and chronic diseases (Jayle and Boussier, 1955; Allison and Blumberg, 1958). A simple colorimetric procedure for the determination of serum haptoglobins is presented. It is based on the peroxidase activity of haptoglobin-methaemoglobin complexes.

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References

JAYLE M . [Method for the determination of serum haptoglobin]. Bull Soc Chim Biol (Paris). 1951; 33(7):876-80. View

LAURELL C, Nyman M . Studies on the serum haptoglobin level in hemoglobinemia and its influence on renal excretion of hemoglobin. Blood. 1957; 12(6):493-506. View

Nyman M . [Haptoglobin determination in serum, normal concentrations and relation to Smithies' serum groups]. Clin Chim Acta. 1958; 3(1):111-3. DOI: 10.1016/0009-8981(58)90067-6. View

Allison A, Blumberg B . The genetically determined serum hepatoglobins in rheumatoid arthritis. Arthritis Rheum. 1958; 1(3):239-43. DOI: 10.1002/art.1780010306. View

NOSSLIN B, Nyman M . Haptoglobin determination in diagnosis of haemolytic diseases. Lancet. 1958; 1(7028):1000-1. DOI: 10.1016/s0140-6736(58)91804-x. View