The Cerebrospinal Fluid Choline Levels in Patients with Huntington's Chorea. Negative Effect of Haloperidol Treatment
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Psychiatry
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Lumbar cerebrospinal fluid (CSF) choline (CH) levels were measured in patients with Huntington's chorea (n = 14). This group was found not to differ significantly from normal controls (n = 13). The values for lumbar CSF Ch levels in the normal subjects were comparable with previously reported values. Of the choreic patients, seven were put on haloperidol treatment (4--6 mg daily). The CSF choline level remained unchanged with this treatment after 20 days. CSF cholinesterase activity was measured in the control and choreic group. The results were not significantly different.
2-dimethylaminoethanol (Deanol) in Huntington's chorea.
Caraceni T, Girotti F, Celano I, Parati E, Balboni L J Neurol Neurosurg Psychiatry. 1978; 41(12):1114-8.
PMID: 153384 PMC: 493240. DOI: 10.1136/jnnp.41.12.1114.