SEQUENTIAL GENE ACTION IN THE ESTABLISHMENT OF LYSOGENY

Overview

Journal Science

Specialty Science

Date 1964 Dec 18

PMID 14224500

Citations 19

Authors

M Levine

H O Smith

Affiliations

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Abstract

A study of temperature sensitive clear-plaque-forming mutants of bacteriophage P22 demonstrates that the c(1) and c(2) loci must function in a temporal sequence in the establishment of lysogeny in Salmonella typhimurium. The c(1) locus acts for only a 4-minute interval between the 7th to 11th minute of the infection. The c(2) locus begins to function some minutes later, and its continued activity is necessary for perpetuation of the lysogenic state.

Citing Articles

Lateral transduction is inherent to the life cycle of the archetypical Salmonella phage P22.

Fillol-Salom A, Bacigalupe R, Humphrey S, Chiang Y, Chen J, Penades J Nat Commun. 2021; 12(1):6510.

PMID: 34751192 PMC: 8575938. DOI: 10.1038/s41467-021-26520-4.

in vitro MORPHOGENESIS OF PHAGE P22 FROM HEADS AND BASE-PLATE PARTS.

Israel J, ANDERSON T, Levine M Proc Natl Acad Sci U S A. 1967; 57(2):284-91.

PMID: 16591466 PMC: 335502. DOI: 10.1073/pnas.57.2.284.

Induction of lambdoid prophages by amino acid deprivation: differential inducibility; role of recA.

MELECHEN N, Go G Mol Gen Genet. 1980; 180(1):147-55.

PMID: 6449654 DOI: 10.1007/BF00267364.

Second locus of bacteriophage P22 necessary for the maintenance of lysogeny.

Gough M J Virol. 1968; 2(10):992-8.

PMID: 5723705 PMC: 375429. DOI: 10.1128/JVI.2.10.992-998.1968.

Control of the replication complex of bacteriophage P22.

Levine M, Chakravorty M, Bronson M J Virol. 1970; 6(4):400-5.

PMID: 5497885 PMC: 376136. DOI: 10.1128/JVI.6.4.400-405.1970.