LOCALIZATION OF CALCIUM-ACCUMULATING STRUCTURES IN STRIATED MUSCLE FIBERS

Overview

Journal Science

Specialty Science

Date 1965 Jan 8

PMID 14220445

Citations 72

Authors

L L COSTANTIN

C Franzini-Armstrong

R J PODOLSKY

Affiliations

Soon will be listed here.

Abstract

When frog muscle fibers from which the sarcolemma had been dissected away were perfused with a calcium solution and then treated with oxalate, electron-opaque material, probably calcium oxalate, accumulated in the terminal sacs of the sarcoplasmic reticulum. These regions of calcium accumulation were identified with the intracellular calcium sink that controls the relaxation phase of the contraction-relaxation cycle; their proximity to tubules implicated in intracellular stimulus conduction suggests that they might also be regions from which calcium is released to trigger contraction.

Citing Articles

Electron microscopy of cardiac 3D nanodynamics: form, function, future.

Kohl P, Greiner J, Rog-Zielinska E Nat Rev Cardiol. 2022; 19(9):607-619.

PMID: 35396547 DOI: 10.1038/s41569-022-00677-x.

Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?.

Louch W, Perdreau-Dahl H, Edwards A Front Physiol. 2022; 13:834211.

PMID: 35356084 PMC: 8959215. DOI: 10.3389/fphys.2022.834211.

The interaction of Ca2+ with sarcomeric proteins: role in function and dysfunction of the heart.

ter Keurs H Am J Physiol Heart Circ Physiol. 2011; 302(1):H38-50.

PMID: 22021327 PMC: 3334233. DOI: 10.1152/ajpheart.00219.2011.

The location of sodium in the transverse tubules of skeletal muscle.

Zadunaisky J J Cell Biol. 2009; 31(2):C11-6.

PMID: 19866707 PMC: 2107050. DOI: 10.1083/jcb.31.2.c11.

III. Electron microscopic radioautographic study of the rat heart perfused with tritiated oleic acid.

Stein O, STEIN Y J Cell Biol. 2009; 36(1):63-77.

PMID: 19806694 PMC: 2107340.