Diseases Associated with HTLV-I: Virus, IL-2 Receptor Dysregulation and Redox Regulation

Overview

Journal Immunol Today

Specialty Allergy & Immunology

Date 1992 Oct 1

PMID 1418377

Citations 31

Authors

J Yodoi

T Uchiyama

Affiliations

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Abstract

HTLV-I, the etiological agent in adult T-cell leukemia, has also been strongly implicated in a number of non-neoplastic T-cell-associated diseases. Here, Junji Yodoi and Takashi Uchiyama review these associations and focus on the emerging concepts of IL-2R dysregulation and redox regulation by adult T-cell leukemia-derived factor in the pathogenesis of HTLV-I-related diseases.

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