HEMOGLOBIN G-COUSHATTA: A NEW VARIANT IN AN AMERICAN INDIAN FAMILY

Overview

Journal Science

Specialty Science

Date 1964 Feb 14

PMID 14081243

Citations 5

Authors

R G SCHNEIDER

M E HAGGARD

C W McNUTT

J E JOHNSON Jr

Affiliations

Soon will be listed here.

Abstract

A new hemoglobin variant, G(couhatta) (alpha2(A) beta2(iiiglu-->ala)), has been found in three generations of a family from the Alabama Coushatta Indian tribe in east Texas. The propositus suffers from an apparently unrelated, possibly genetic, agranulocytosis. According to the history and the blood grouping data there is considerable in breeding in the tribe and remarkably little admixture with other ethnic groups.

Citing Articles

Estimating the age of Hb G-Coushatta [β22(B4)Glu→Ala] mutation by haplotypes of β-globin gene cluster in Denizli, Turkey.

Ozturk O, Arikan S, Atalay A, Atalay E Mol Genet Genomic Med. 2018; .

PMID: 29717566 PMC: 6081228. DOI: 10.1002/mgg3.404.

Study on hemoglobinopathies in Hubei Province: report of hemoglobin GCoushatta homozygotes and hemoglobin GTaibei heterozygotes.

Wang B, Gu Y, Luo Y, Yang A, Zeng Y, Huang S Acta Acad Med Wuhan. 1982; 2(1):1-7.

PMID: 7170081 DOI: 10.1007/BF02858842.

High incidence of haemoglobin G Accra in a rural district in Jamaica.

Milner P J Med Genet. 1967; 4(2):88-90.

PMID: 5619995 PMC: 1468542. DOI: 10.1136/jmg.4.2.88.

Haemoglobin D Punjab (D Los Angeles).

Vella F, Lehmann H J Med Genet. 1974; 11(4):341-8.

PMID: 4613830 PMC: 1013202. DOI: 10.1136/jmg.11.4.341.

Partial mispairing and crossing-over between beta 0 and delta genes as the origin of the delta beta 0 thalassemia gene. A single mutational event hypothesis.

Cantu J, Ibarra B, Vaca G, Ramirez M, Sanchez-Corona J Hum Genet. 1979; 49(2):191-8.

PMID: 468250 DOI: 10.1007/BF00277642.