The Effect of Exercise on Levodopa Absorption

Overview

Journal Neurology

Specialty Neurology

Date 1992 Oct 1

PMID 1407589

Citations 8

Authors

J H Carter

J G Nutt

W R Woodward

Affiliations

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Abstract

We studied the effect of exercise using cycle ergometry on levodopa absorption in ten patients with Parkinson's disease. Oral levodopa was administered during exercise and at rest on separate days. Exercise delayed levodopa absorption in five patients, increased it in three, and did not influence it in two. We conclude that exercise can either increase or decrease levodopa absorption.

Citing Articles

Impact of Physical Exercise on Levodopa Therapy Across Parkinson's Disease Stages.

Figura M, Mrozowicz A, Milanowski L, Szlufik S, Rackowska E, Lypkan H J Parkinsons Dis. 2024; 14(5):1039-1049.

PMID: 38905055 PMC: 11307027. DOI: 10.3233/JPD-230384.

Responsiveness of respiratory function in Parkinson's Disease to an integrative exercise programme: A prospective cohort study.

McMahon L, McGrath D, Blake C, Lennon O PLoS One. 2024; 19(3):e0301433.

PMID: 38551984 PMC: 10980210. DOI: 10.1371/journal.pone.0301433.

Rationale and Design of the PAIRED Trial: Partnered Dance Aerobic Exercise as a Neuroprotective, Motor, and Cognitive Intervention in Parkinson's Disease.

Hackney M, Bay A, Jackson J, Nocera J, Krishnamurthy V, Crosson B Front Neurol. 2020; 11:943.

PMID: 33162925 PMC: 7581698. DOI: 10.3389/fneur.2020.00943.

Guidelines on exercise testing and prescription for patients at different stages of Parkinson's disease.

Martignon C, Pedrinolla A, Ruzzante F, Giuriato G, Laginestra F, Bouca-Machado R Aging Clin Exp Res. 2020; 33(2):221-246.

PMID: 32514871 DOI: 10.1007/s40520-020-01612-1.

The role of exercise in facilitating basal ganglia function in Parkinson's disease.

Petzinger G, Fisher B, Akopian G, Holschneider D, Wood R, Walsh J Neurodegener Dis Manag. 2013; 1(2):157-170.

PMID: 23805167 PMC: 3691073. DOI: 10.2217/nmt.11.16.