Genetic Recombination in Brome Mosaic Virus: Effect of Sequence and Replication of RNA on Accumulation of Recombinants

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1992 Nov 1

PMID 1404621

Citations 29

Authors

P D Nagy

J J Bujarski

Affiliations

Soon will be listed here.

Abstract

In order to facilitate the isolation of recombinants in brome mosaic virus, a series of duplication mutants with alterations in the RNA3 3' noncoding region has been engineered. The distribution of crossovers, which was observed to be dependent on the parental RNA3 sequence, supported the role of RNA structure in recombination. However, a negative correlation between replication of the parental RNA3 constructs and the accumulation of recombinant progeny confirmed the role of selection.

Citing Articles

Emergence of distinct brome mosaic virus recombinants is determined by the polarity of the inoculum RNA.

Kwon S, Rao A J Virol. 2012; 86(9):5204-20.

PMID: 22357282 PMC: 3347362. DOI: 10.1128/JVI.00351-12.

Recombination of 5' subgenomic RNA3a with genomic RNA3 of Brome mosaic bromovirus in vitro and in vivo.

Sztuba-Solinska J, Dzianott A, Bujarski J Virology. 2010; 410(1):129-41.

PMID: 21111438 PMC: 7111948. DOI: 10.1016/j.virol.2010.10.037.

Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor.

Li Z, Pogany J, Panavas T, Xu K, Esposito A, Kinzy T Virology. 2009; 385(1):245-60.

PMID: 19131084 PMC: 2785496. DOI: 10.1016/j.virol.2008.11.041.

Characterization of a novel 5' subgenomic RNA3a derived from RNA3 of Brome mosaic bromovirus.

Wierzchoslawski R, Urbanowicz A, Dzianott A, Figlerowicz M, Bujarski J J Virol. 2006; 80(24):12357-66.

PMID: 17005659 PMC: 1676258. DOI: 10.1128/JVI.01207-06.

Suppression of viral RNA recombination by a host exoribonuclease.

Cheng C, Serviene E, Nagy P J Virol. 2006; 80(6):2631-40.

PMID: 16501073 PMC: 1395426. DOI: 10.1128/JVI.80.6.2631-2640.2006.

References

Bujarski J, Dreher T, Hall T . Deletions in the 3'-terminal tRNA-like structure of brome mosaic virus RNA differentially affect aminoacylation and replication in vitro. Proc Natl Acad Sci U S A. 1985; 82(17):5636-40. PMC: 390606. DOI: 10.1073/pnas.82.17.5636. View

Dreher T, Hall T . Mutational analysis of the sequence and structural requirements in brome mosaic virus RNA for minus strand promoter activity. J Mol Biol. 1988; 201(1):31-40. DOI: 10.1016/0022-2836(88)90436-6. View

Palasingam K, Shaklee P . Reversion of Q beta RNA phage mutants by homologous RNA recombination. J Virol. 1992; 66(4):2435-42. PMC: 289039. DOI: 10.1128/JVI.66.4.2435-2442.1992. View

Mindich L, Qiao X, Onodera S, Gottlieb P, Strassman J . Heterologous recombination in the double-stranded RNA bacteriophage phi 6. J Virol. 1992; 66(5):2605-10. PMC: 241013. DOI: 10.1128/JVI.66.5.2605-2610.1992. View

Banner L, Lai M . Random nature of coronavirus RNA recombination in the absence of selection pressure. Virology. 1991; 185(1):441-5. PMC: 7131166. DOI: 10.1016/0042-6822(91)90795-d. View

Cascone P, Carpenter C, Li X, Simon A . Recombination between satellite RNAs of turnip crinkle virus. EMBO J. 1990; 9(6):1709-15. PMC: 551873. View

Zhang C, Cascone P, Simon A . Recombination between satellite and genomic RNAs of turnip crinkle virus. Virology. 1991; 184(2):791-4. DOI: 10.1016/0042-6822(91)90454-j. View

van der Kuyl A, Neeleman L, Bol J . Complementation and recombination between alfalfa mosaic virus RNA3 mutants in tobacco plants. Virology. 1991; 183(2):731-8. PMC: 7173233. DOI: 10.1016/0042-6822(91)91002-x. View

Goulden M, Lomonossoff G, Wood K, Davies J . A model for the generation of tobacco rattle virus (TRV) anomalous isolates: pea early browning virus RNA-2 acquires TRV sequences from both RNA-1 and RNA-2. J Gen Virol. 1991; 72 ( Pt 7):1751-4. DOI: 10.1099/0022-1317-72-7-1751. View

10.

Rott M, Tremaine J, Rochon D . Comparison of the 5' and 3' termini of tomato ringspot virus RNA1 and RNA2: evidence for RNA recombination. Virology. 1991; 185(1):468-72. PMC: 7172098. DOI: 10.1016/0042-6822(91)90801-h. View

11.

Shapira R, Choi G, Hillman B, Nuss D . The contribution of defective RNAs to the complexity of viral-encoded double-stranded RNA populations present in hypovirulent strains of the chestnut blight fungus Cryphonectria parasitica. EMBO J. 1991; 10(4):741-6. PMC: 452711. DOI: 10.1002/j.1460-2075.1991.tb08005.x. View

12.

Ishikawa M, Kroner P, Ahlquist P, Meshi T . Biological activities of hybrid RNAs generated by 3'-end exchanges between tobacco mosaic and brome mosaic viruses. J Virol. 1991; 65(7):3451-9. PMC: 241328. DOI: 10.1128/JVI.65.7.3451-3459.1991. View

13.

Bujarski J, Dzianott A . Generation and analysis of nonhomologous RNA-RNA recombinants in brome mosaic virus: sequence complementarities at crossover sites. J Virol. 1991; 65(8):4153-9. PMC: 248849. DOI: 10.1128/JVI.65.8.4153-4159.1991. View

14.

Allison R, Thompson C, Ahlquist P . Regeneration of a functional RNA virus genome by recombination between deletion mutants and requirement for cowpea chlorotic mottle virus 3a and coat genes for systemic infection. Proc Natl Acad Sci U S A. 1990; 87(5):1820-4. PMC: 53575. DOI: 10.1073/pnas.87.5.1820. View

15.

Rao A, Sullivan B, Hall T . Use of Chenopodium hybridum facilitates isolation of brome mosaic virus RNA recombinants. J Gen Virol. 1990; 71 ( Pt 6):1403-7. DOI: 10.1099/0022-1317-71-6-1403. View

16.

Bujarski J, Kaesberg P . Genetic recombination between RNA components of a multipartite plant virus. Nature. 1986; 321(6069):528-31. PMC: 7095370. DOI: 10.1038/321528a0. View

17.

Kroner P, Richards D, Traynor P, Ahlquist P . Defined mutations in a small region of the brome mosaic virus 2 gene cause diverse temperature-sensitive RNA replication phenotypes. J Virol. 1989; 63(12):5302-9. PMC: 251196. DOI: 10.1128/JVI.63.12.5302-5309.1989. View

18.

Dawson W, Lewandowski D, Hilf M, Bubrick P, Raffo A, Shaw J . A tobacco mosaic virus-hybrid expresses and loses an added gene. Virology. 1989; 172(1):285-92. DOI: 10.1016/0042-6822(89)90130-x. View

19.

Tolskaya E, Romanova L, Blinov V, Viktorova E, Sinyakov A, Kolesnikova M . Studies on the recombination between RNA genomes of poliovirus: the primary structure and nonrandom distribution of crossover regions in the genomes of intertypic poliovirus recombinants. Virology. 1987; 161(1):54-61. DOI: 10.1016/0042-6822(87)90170-x. View

20.

Kirkegaard K, Baltimore D . The mechanism of RNA recombination in poliovirus. Cell. 1986; 47(3):433-43. PMC: 7133339. DOI: 10.1016/0092-8674(86)90600-8. View