Characterisation of a Novel Repetitive DNA Sequence from Mycobacterium Bovis

Overview

Journal FEMS Microbiol Lett

Publisher Oxford University Press

Specialty Microbiology

Date 1992 Sep 15

PMID 1398035

Citations 6

Authors

T J Doran

A L Hodgson

J K Davies

A J Radford

Affiliations

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Abstract

We report characterisation of three copies of a novel repeat sequence isolated from a Mycobacterium bovis genomic library. The repeat occurs within open reading frames, potentially encoding a conserved tandem array of a pentapeptide sequence with the consensus X-Gly-Asn-X-Gly. The tandem array is present up to five times in M. bovis and it is proposed that they may occur in a family of genes expressing functionally related proteins. We postulate that these proteins may play a role in binding of M. bovis to host cell receptors.

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