Studies of Org 10172 in Patients with Acute Ischemic Stroke. TOAST Study Group

Overview

Journal Haemostasis

Specialties Cardiology & Vascular Diseases
Hematology

Date 1992 Jan 11

PMID 1379970

Citations 13

Authors

H P Adams Jr

R F Woolson

J Biller

W Clarke

Affiliations

Soon will be listed here.

Abstract

This report presents data from pilot studies of Org 10172 in the management of patients with acute ischemic stroke. The studies have established a potentially optimal dosage and treatment regimen and have provided information for the development of a large randomized trial. The trial of Org 10172 in acute stroke treatment is now underway in the United States.

Citing Articles

Transcatheter PFO closure for cryptogenic stroke: current approaches and future considerations.

Eltelbany M, Gattani R, Ofosu-Somuah A, Damluji A, Epps K, Batchelor W Front Cardiovasc Med. 2024; 11:1391886.

PMID: 38832314 PMC: 11144870. DOI: 10.3389/fcvm.2024.1391886.

Pontine autosomal dominant microangiopathy with leukoencephalopathy: Col4A1 gene variants in the original family and sporadic stroke.

Roos J, Muller S, Giese A, Appenzeller S, Ringelstein E, Fiehler J J Neurol. 2023; 270(5):2631-2639.

PMID: 36786861 PMC: 10130117. DOI: 10.1007/s00415-023-11590-9.

Fibromuscular Dysplasia/Carotid Web in Angio-CT Imaging: A Rare Cause of Ischemic Stroke.

Rzepka M, Chmiela T, Bosowska J, Cebula M, Krzystanek E Medicina (Kaunas). 2021; 57(10).

PMID: 34684149 PMC: 8539851. DOI: 10.3390/medicina57101112.

A topical heparinoid-containing product improves epidermal permeability barrier homeostasis in mice.

Yao Y, Guo P, Feng X, Shen C, Huang J, Zhang J Exp Dermatol. 2019; 28(8):956-960.

PMID: 31168829 PMC: 6663615. DOI: 10.1111/exd.13985.

Rheumatoid arthritis significantly increased recurrence risk after ischemic stroke/transient ischemic attack.

Chen Y, Hsieh F, Lien L, Hu C, Jeng J, Peng G J Neurol. 2018; 265(8):1810-1818.

PMID: 29860668 DOI: 10.1007/s00415-018-8885-9.