Surgical Excision of Subfoveal Neovascular Membranes in Age-related Macular Degeneration

Overview

Journal Am J Ophthalmol

Specialty Ophthalmology

Date 1992 Mar 25

PMID 1371906

Citations 36

Authors

H M Lambert

A Capone Jr

T M AABERG

P Sternberg Jr

B A Mandell

P F Lopez

Affiliations

Soon will be listed here.

Abstract

We studied the results of surgical excision of ten consecutive subfoveal choroidal neovascular membranes in ten patients with age-related macular degeneration. The criteria for surgical eligibility included the following: (1) a clearly identifiable subfoveal membrane occupying the entire foveal avascular zone, (2) a visual acuity of 20/200 or worse, (3) minimal subretinal hemorrhage, and (4) an associated exudative macular detachment. Six of the ten patients showed visual improvement at one-month and three-month follow-up visits and seven showed visual improvement by the six-month examination. All ten maculae remained attached without recurrence of subfoveal neovascular membranes throughout the follow-up period. These results suggested that surgical excision is a viable alternative to laser photocoagulation in patients with subfoveal neovascularization in age-related macular degeneration.

Citing Articles

A new kind of labyrinth-like capillary is responsible for leakage from human choroidal neovascular endothelium, as investigated by high-resolution electron microscopy.

Schraermeyer U, Julien S, Biesemeier A, Bartz-Schmidt K, Wolburg H Graefes Arch Clin Exp Ophthalmol. 2014; 253(5):681-9.

PMID: 25042819 DOI: 10.1007/s00417-014-2733-0.

Clinical applications of optical coherence tomography in the posterior pole: the 2011 José Manuel Espino Lecture - Part II.

Fernando Arevalo J, Lasave A, Arias J, Serrano M, Arevalo F Clin Ophthalmol. 2013; 7:2181-206.

PMID: 24235811 PMC: 3825852. DOI: 10.2147/OPTH.S51158.

Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration.

Albert D, Neekhra A, Wang S, Darjatmoko S, Sorenson C, Dubielzig R Arch Ophthalmol. 2010; 128(2):212-22.

PMID: 20142545 PMC: 2820133. DOI: 10.1001/archophthalmol.2009.395.

Physiology of vitreous surgery.

Stefansson E Graefes Arch Clin Exp Ophthalmol. 2008; 247(2):147-63.

PMID: 19034481 DOI: 10.1007/s00417-008-0980-7.

The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results.

Mojana F, Cheng L, Bartsch D, Silva G, Kozak I, Nigam N Am J Ophthalmol. 2008; 146(2):218-227.

PMID: 18538742 PMC: 2735863. DOI: 10.1016/j.ajo.2008.04.027.