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DNA Structure, Mutations, and Human Genetic Disease

Overview
Publisher Elsevier
Specialty Biotechnology
Date 1992 Dec 1
PMID 1369117
Citations 46
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Abstract

The etiology of fragile X syndrome, myotonic dystrophy and Kennedy's disease has been attributed to the massive expansion of triplet repeat DNA sequences. This review details the relationships between the structural diversity of DNA, its secondary structure or DNA-directed mutagenesis, and the expansion of triplet repeats.

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