Use of Mecamylamine in the Management of Hypertension

Overview

Journal Br Med J

Specialty General Medicine

Date 1957 Feb 23

PMID 13396275

Citations 7

Authors

E G McQueen

F H Smirk

Affiliations

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Citing Articles

The Antinociceptive and Anti-Inflammatory Properties of the 7 nAChR Weak Partial Agonist -CF ,-diethyl-'-phenylpiperazine.

Quadri M, Bagdas D, Toma W, Stokes C, Horenstein N, Damaj M J Pharmacol Exp Ther. 2018; 367(2):203-214.

PMID: 30111636 PMC: 7593094. DOI: 10.1124/jpet.118.249904.

An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.

Baakman A, Alvarez-Jimenez R, Rissmann R, Klaassen E, Stevens J, Goulooze S Br J Clin Pharmacol. 2017; 83(8):1676-1687.

PMID: 28217868 PMC: 5510063. DOI: 10.1111/bcp.13268.

Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo.

Rahman S, Zhang Z, Papke R, Crooks P, Dwoskin L, Bardo M Br J Pharmacol. 2007; 153(4):792-804.

PMID: 18059317 PMC: 2259212. DOI: 10.1038/sj.bjp.0707612.

DEPRESSION OF THE VASOMOTOR CENTRE BY MECAMYLAMINE, INDEPENDENT OF ITS GANGLION-BLOCKING ACTIVITY.

Bhargava K, DHAWAN K Br J Pharmacol Chemother. 1963; 21:39-44.

PMID: 14066149 PMC: 1703867. DOI: 10.1111/j.1476-5381.1963.tb01499.x.

Treatment of hypertension with pentolinium and mecamylamine.

Sears H, Snow P, Houston I Br Med J. 1959; 1(5120):462-5.

PMID: 13629020 PMC: 1992771. DOI: 10.1136/bmj.1.5120.462.

References

Smirk F, Alstad K . Treatment of arterial hypertension by penta- and hexamethonium salts; based on 150 tests on hypertensives of varied aetiology and 53 patients treated for periods of two to fourteen months. Br Med J. 1951; 1(4717):1217-28. PMC: 2069107. DOI: 10.1136/bmj.1.4717.1217. View

Smirk F . Action of a new methonium compound in arterial hypertension; pentamethylene 1 : 5-bis-n-(n-methyl-pyrrolidinium) bitartrate (M. & B. 2050A). Lancet. 1953; 1(6758):457-64. DOI: 10.1016/s0140-6736(53)91640-7. View

RESTALL P, Smirk F . The treatment of high blood pressure with hexamethonium iodide. N Z Med J. 1950; 49(271):206-9. View