Viral Agents Associated with Infantile Gastroenteritis in Nigeria: Relative Prevalence of Adenovirus Serotypes 40 and 41, Astrovirus, and Rotavirus Serotypes 1 to 4
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Sixty-six stool specimens from infants with diarrhoea in Nigeria were examined for the presence of viral pathogens. Rotaviruses were found in 25.8% of specimens and astroviruses in 1.5%. Serotypes were determined for 47.1% of the rotavirus positive specimens, all of which were serotype 1. RNA analysis revealed no unusual electrophoretic profiles. No enteric adenoviruses were detected. In contrast, in a parallel study conducted in the UK, rotaviruses (including serotypes 1, 2 and 4) accounted for 21.9% of infections, adenovirus serotypes 40 and 41 13.6%, and astroviruses 4.5%.
Digwo D, Chidebelu P, Ugwu K, Adediji A, Farkas K, Chigor V Pathog Glob Health. 2022; 117(1):24-35.
PMID: 35249468 PMC: 9848363. DOI: 10.1080/20477724.2022.2043223.
Astrovirus infection in children in lagos, Nigeria.
Ayolabi C, Ojo D, Akpan I Afr J Infect Dis. 2013; 6(1):1-4.
PMID: 23878708 PMC: 3555437. DOI: 10.4314/ajid.v6i1.77733.
Li D, He M, Jiang S Appl Environ Microbiol. 2010; 76(5):1442-8.
PMID: 20080992 PMC: 2832376. DOI: 10.1128/AEM.01937-09.
Detection of infectious adenovirus in cell culture by mRNA reverse transcription-PCR.
Ko G, Cromeans T, Sobsey M Appl Environ Microbiol. 2003; 69(12):7377-84.
PMID: 14660388 PMC: 309946. DOI: 10.1128/AEM.69.12.7377-7384.2003.
Cunliffe N, Kilgore P, Bresee J, Steele A, Luo N, Hart C Bull World Health Organ. 1998; 76(5):525-37.
PMID: 9868844 PMC: 2305791.