A Comparison of the Effects of Hexamethonium Alone and in Combination with 1-hydrazinophthalazine (apresoline) in the Treatment of Hypertension

Overview

Journal Trans Am Clin Climatol Assoc

Specialty Rehabilitation Medicine

Date 1953 Jan 1

PMID 13205635

Authors

E S ORGAIN

C L RAST Jr

H A SIEBER

Affiliations

Soon will be listed here.

References

Blainey J . Hexamethonium compounds in the treatment of hypertension. Lancet. 1952; 1(6716):993-6. DOI: 10.1016/s0140-6736(52)90641-7. View

Moyer J . Hydrallazine (apresoline) hydrochloride; pharmacological observations and clinical results in the therapy of hypertension. AMA Arch Intern Med. 1953; 91(4):419-39. DOI: 10.1001/archinte.1953.00240160005002. View

Campbell A, Graham J, Maxwell R . Treatment of hypertension by oral methonium compounds. Br Med J. 1952; 1(4752):251-4. PMC: 2022618. DOI: 10.1136/bmj.1.4752.251. View

Moyer J, MILLER S, FORD R . Orally administered hexamethonium chloride in hypertension. J Am Med Assoc. 1953; 152(12):1121-9. DOI: 10.1001/jama.1953.03690120037010. View

Schroeder H, Morrow J . The control of arterial hypertension by hyphex, with an evaluation of other methods of therapy. Med Clin North Am. 1953; 1(Nationwide Number):991-1008. DOI: 10.1016/s0025-7125(16)34973-2. View

Smirk F, Alstad K . Treatment of arterial hypertension by penta- and hexamethonium salts; based on 150 tests on hypertensives of varied aetiology and 53 patients treated for periods of two to fourteen months. Br Med J. 1951; 1(4717):1217-28. PMC: 2069107. DOI: 10.1136/bmj.1.4717.1217. View

FREIS E, Finnerty Jr F, SCHNAPER N, Johnson R . The treatment of hypertension with hexamethonium. Circulation. 1952; 5(1):20-7. DOI: 10.1161/01.cir.5.1.20. View

SCHROEDER N . The effect of 1-hydrasinophthalasine in hypertension. Circulation. 1952; 5(1):28-37. DOI: 10.1161/01.cir.5.1.28. View

Taylor R, DUSTAN H, CORCORAN A, PAGE I . Evaluation of l-hydrazinophthalazine (apresoline) in treatment of hypertensive disease. AMA Arch Intern Med. 1952; 90(6):734-49. DOI: 10.1001/archinte.1952.00240120009002. View

10.

Johnson R, FREIS E, Schnaper H . Clinical evaluation of 1-hydrazinophthalazine (C-5968) in hypertension, with special reference to alternating treatment with hexamethonium. Circulation. 1952; 5(6):833-41. DOI: 10.1161/01.cir.5.6.833. View

11.

HILKER R, RHOADS P, BILLINGS C . Clinical use of hydralazine and hexamethonium in treatment of hypertension. J Am Med Assoc. 1953; 153(1):5-9. DOI: 10.1001/jama.1953.02940180007002. View

12.

REUBI F . Renal hyperemia induced in man by a new phthalazine derivative. Proc Soc Exp Biol Med. 1950; 73(1):102. DOI: 10.3181/00379727-73-17591. View

13.

Hafkenschiel J, LINDAUER M . 1-Hydrazinophthalazine; apresoline in the treatment of hypertension: a two year study. Circulation. 1953; 7(1):52-7. DOI: 10.1161/01.cir.7.1.52. View

14.

PALMER R, LOOFBOUROW D, Doering C . Prognosis in essential hypertension; 8-year follow-up study of 430 patients on conventional medical treatment. N Engl J Med. 1948; 239(26):990-4. DOI: 10.1056/NEJM194812232392602. View

15.

Schroeder H . Control of hypertension by hexamethonium and 1-hydrazinophthalazine; preliminary observations. AMA Arch Intern Med. 1952; 89(4):523-40. DOI: 10.1001/archinte.1952.00240040002001. View

16.

GRIMSON K, ORGAIN E, ROWE Jr C, SIEBER H . Caution with regard to use of hexamethonium and "apresoline". J Am Med Assoc. 1952; 149(3):215-20. DOI: 10.1001/jama.1952.02930200001001. View