Effect of X-537A- on the Phosphorylated Protein in Sarcoplasmic Reticulum Vesicles

Overview

Journal Experientia

Specialty Science

Date 1976 Apr 15

PMID 131696

Citations 1

Authors

V R Osorio e Castro

M G Vale

A P Carvalho

Affiliations

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Abstract

The effect of the antibiotic X537A on the phosphorylated ATPase (E approximately P) was investigated. The results show that X-537A depresses the level of E approximately P which is dependent on the Ca2+ gradient, while the Ca2+-independent E approximately P is not affected.

Citing Articles

Effect of temperature on the reversal of the calcium ion pump in sarcoplasmic reticulum.

Vale M, Carvalho A Biochem J. 1980; 186(2):461-7.

PMID: 7378062 PMC: 1161597. DOI: 10.1042/bj1860461.

References

Masuda H, De Meis L . Phosphorylation of the sarcoplasmic reticulum membrane by orthophosphate. Inhibition by calcium ions. Biochemistry. 1973; 12(23):4581-5. DOI: 10.1021/bi00747a006. View

Scarpa A, Inesi G . Ionophore mediated equilibration of calcium ion gradients in fragmented-sarcoplasmic reticulum. FEBS Lett. 1972; 22(3):273-276. DOI: 10.1016/0014-5793(72)80248-5. View

De Meis L, Masuda H . Phosphorylation of the sarcoplasmic reticulum membrane by orthophosphate through two different reactions. Biochemistry. 1974; 13(10):2057-62. DOI: 10.1021/bi00707a009. View

Scarpa A, Baldassare J, Inesi G . The effect of calcium ionophores on fragmented sarcoplasmic reticulum. J Gen Physiol. 1972; 60(6):735-49. PMC: 2226096. DOI: 10.1085/jgp.60.6.735. View

De Meis L . Phosphorylation of the membranous protein of the sarcoplasmic reticulum. Inhibition by Na + and K + . Biochemistry. 1972; 11(13):2460-5. DOI: 10.1021/bi00763a012. View

Caswell A, PRESSMAN B . Kinetics of transport of divalent cations across sarcoplasmic reticulum vesicles induced by ionophores. Biochem Biophys Res Commun. 1972; 49(1):292-8. DOI: 10.1016/0006-291x(72)90043-5. View

Panet R, SELINGER Z . Synthesis of ATP coupled to Ca 2+ release from sarcoplasmic reticulum vesicles. Biochim Biophys Acta. 1972; 255(1):34-42. DOI: 10.1016/0005-2736(72)90005-3. View

PRESSMAN B . Properties of ionophores with broad range cation selectivity. Fed Proc. 1973; 32(6):1698-703. View

Yamamoto T, Tonomura Y . Reaction mechanism of the Ca++ -dependent ATPase of sarcoplasmic reticulum from skeletal muscle. I. Kinetic studies. J Biochem. 1967; 62(5):558-75. DOI: 10.1093/oxfordjournals.jbchem.a128706. View

10.

Yamada S, Tonomura Y . Phosphorylation of the Ca 2+ -Mg 2+ -dependent ATPase of the sarcoplasmic reticulum coupled with cation translocation. J Biochem. 1972; 71(6):1101-4. DOI: 10.1093/oxfordjournals.jbchem.a129863. View

11.

MAKINOSE M, Hasselbach W . ATP synthesis by the reverse of the sarcoplasmic calcium pump. FEBS Lett. 1971; 12(5):271-272. DOI: 10.1016/0014-5793(71)80196-5. View

12.

Kanazawa T, Yamada S, Tonomura Y . ATP formation from ADP and a phosphorylated intermediate of Ca2+-dependent ATPase in fragmented sarcoplasmic reticulum. J Biochem. 1970; 68(4):593-5. DOI: 10.1093/oxfordjournals.jbchem.a129392. View

13.

Deamer D, Baskin R . ATP synthesis in sarcoplasmic reticulum. Arch Biochem Biophys. 1972; 153(1):47-54. DOI: 10.1016/0003-9861(72)90418-3. View

14.

Entman M, Gillette P, Wallick E, PRESSMAN B, Schwartz A . A study of calcium binding and uptake by isolated cardiac sarcoplasmic reticulum: the use of a new ionophore (X537A). Biochem Biophys Res Commun. 1972; 48(4):847-53. DOI: 10.1016/0006-291x(72)90685-7. View

15.

Martonosi A . Sarcoplasmic reticulum. VII. Properties of a phosphoprotein intermediate implicated in calcium transport. J Biol Chem. 1969; 244(4):613-20. View

16.

MAKINOSE M . The phosphorylation of the membranal protein of the sarcoplasmic vesicles during active calcium transport. Eur J Biochem. 1969; 10(1):74-82. View

17.

MAKINOSE M . Phosphoprotein formation during osmo-chemical energy conversion in the membrane of the sarcoplasmic reticulum. FEBS Lett. 1972; 25(1):113-115. DOI: 10.1016/0014-5793(72)80466-6. View

18.

Yamada S, Sumida M, Tonomura Y . Reaction mechanism of the Ca2+-dependent ATPase of sarcoplasmic reticulum from skeletal muscle. 8. Molecular mechanism of the conversion of osmotic energy to chemical energy in the sarcoplasmic reticulum. J Biochem. 1972; 72(6):1537-48. DOI: 10.1093/oxfordjournals.jbchem.a130045. View

19.

Kanazawa T, BOYER P . Occurrence and characteristics of a rapid exchange of phosphate oxygens catalyzed by sarcoplasmic reticulum vesicles. J Biol Chem. 1973; 248(9):3163-72. DOI: 10.2172/4473783. View

20.

MAKINOSE M . Possible functional states of the enzyme of the sarcoplasmic calcium pump. FEBS Lett. 1973; 37(2):140-3. DOI: 10.1016/0014-5793(73)80443-0. View