Two Hypotheses Reexamined: Gating Currents and the Number of Mobile Ions in the Na+ Channel

Overview

Journal Biophys J

Publisher Cell Press

Specialty Biophysics

Date 1992 Jan 1

PMID 1311611

Authors

F F OFFNER

Affiliations

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References

OFFNER F, Kim S . Conformational effects on the activation free energy of diffusion through membranes as influenced by electric fields. J Theor Biol. 1976; 61(1):97-112. DOI: 10.1016/0022-5193(76)90107-7. View

Neher E, Sakmann B . Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature. 1976; 260(5554):799-802. DOI: 10.1038/260799a0. View

Goldman L . Gating current kinetics in Myxicola giant axons. Order of the back transition rate constants. Biophys J. 1991; 59(3):574-89. PMC: 1281222. DOI: 10.1016/S0006-3495(91)82273-1. View

Stuhmer W, Conti F, Suzuki H, Wang X, Noda M, Yahagi N . Structural parts involved in activation and inactivation of the sodium channel. Nature. 1989; 339(6226):597-603. DOI: 10.1038/339597a0. View

OFFNER F . The excitable membrane. A physiochemical model. Biophys J. 1972; 12(12):1583-629. PMC: 1484164. DOI: 10.1016/S0006-3495(72)86185-X. View

ARMSTRONG C, Bezanilla F . Currents related to movement of the gating particles of the sodium channels. Nature. 1973; 242(5398):459-61. DOI: 10.1038/242459a0. View

Schauf C . Evidence for negative gating charges in Myxicola axons. Biophys J. 1983; 42(3):225-31. PMC: 1329231. DOI: 10.1016/S0006-3495(83)84390-2. View

OFFNER F . Sensitivity of membranes to their environment. Role of stochastic processes. Biophys J. 1984; 46(4):447-61. PMC: 1435018. DOI: 10.1016/S0006-3495(84)84042-4. View

Rees D . Experimental evaluation of the effective dielectric constant of proteins. J Mol Biol. 1980; 141(3):323-6. DOI: 10.1016/0022-2836(80)90184-9. View

10.

ARMSTRONG C . Sodium channels and gating currents. Physiol Rev. 1981; 61(3):644-83. DOI: 10.1152/physrev.1981.61.3.644. View

11.

HODGKIN A, HUXLEY A . A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol. 1952; 117(4):500-44. PMC: 1392413. DOI: 10.1113/jphysiol.1952.sp004764. View

12.

Noda M, Shimizu S, Tanabe T, Takai T, Kayano T, Ikeda T . Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature. 1984; 312(5990):121-7. DOI: 10.1038/312121a0. View

13.

OFFNER F . Kinetics of excitable membranes. Voltage amplification in a diffusion regime. J Gen Physiol. 1970; 56(2):272-96. PMC: 2225855. DOI: 10.1085/jgp.56.2.272. View