Human Platelet-derived Endothelial Cell Growth Factor is Homologous to Escherichia Coli Thymidine Phosphorylase

Overview

Journal Protein Sci

Specialty Biochemistry

Date 1992 May 1

PMID 1304367

Citations 14

Authors

G J Barton

C P Ponting

G Spraggon

C Finnis

D Sleep

Affiliations

Soon will be listed here.

Citing Articles

1,3,4-Oxadiazole: An Emerging Scaffold to Inhibit the Thymidine Phosphorylase as an Anticancer Agent.

Murmu A, Banjare P, Matore B, Roy P, Singh J Curr Med Chem. 2023; 31(38):6227-6250.

PMID: 37438902 DOI: 10.2174/0929867331666230712113943.

Developing Wound Dressings Using 2-deoxy--Ribose to Induce Angiogenesis as a Backdoor Route for Stimulating the Production of Vascular Endothelial Growth Factor.

Dikici S, Yar M, Bullock A, Shepherd J, Roman S, MacNeil S Int J Mol Sci. 2021; 22(21).

PMID: 34768868 PMC: 8583821. DOI: 10.3390/ijms222111437.

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy.

Levene M, Bain M, Moran N, Nirmalananthan N, Poulton J, Scarpelli M J Clin Med. 2019; 8(4).

PMID: 30959750 PMC: 6517976. DOI: 10.3390/jcm8040457.

Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3.

Yue H, Tanaka K, Furukawa T, Karnik S, Li W Biochim Biophys Acta. 2012; 1823(8):1316-23.

PMID: 22668509 PMC: 4133185. DOI: 10.1016/j.bbamcr.2012.05.025.

The dual role of thymidine phosphorylase in cancer development and chemotherapy.

Bronckaers A, Gago F, Balzarini J, Liekens S Med Res Rev. 2009; 29(6):903-53.

PMID: 19434693 PMC: 7168469. DOI: 10.1002/med.20159.

References

Heldin C, Wasteson A, Westermark B . Partial purification and characterization of platelet factors stimulating the multiplication of normal human glial cells. Exp Cell Res. 1977; 109(2):429-37. DOI: 10.1016/0014-4827(77)90023-4. View

Desgranges C, Razaka G, Rabaud M, BRICAUD H . Catabolism of thymidine in human blood platelets: purification and properties of thymidine phosphorylase. Biochim Biophys Acta. 1981; 654(2):211-8. DOI: 10.1016/0005-2787(81)90174-x. View

Walter M, Cook W, Cole L, Short S, Koszalka G, KRENITSKY T . Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution. J Biol Chem. 1990; 265(23):14016-22. DOI: 10.2210/pdb1tpt/pdb. View

Yoshimura A, Kuwazuru Y, Furukawa T, Yoshida H, Yamada K, Akiyama S . Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors. Biochim Biophys Acta. 1990; 1034(1):107-13. DOI: 10.1016/0304-4165(90)90160-x. View

Ishikawa F, Miyazono K, Hellman U, Drexler H, Wernstedt C, Hagiwara K . Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor. Nature. 1989; 338(6216):557-62. DOI: 10.1038/338557a0. View

Usuki K, Heldin N, Miyazono K, Ishikawa F, Takaku F, Westermark B . Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture. Proc Natl Acad Sci U S A. 1989; 86(19):7427-31. PMC: 298077. DOI: 10.1073/pnas.86.19.7427. View

Miyazono K, Okabe T, Urabe A, Takaku F, Heldin C . Purification and properties of an endothelial cell growth factor from human platelets. J Biol Chem. 1987; 262(9):4098-103. View

King G, BUCHWALD S . Characterization and partial purification of an endothelial cell growth factor from human platelets. J Clin Invest. 1984; 73(2):392-6. PMC: 425029. DOI: 10.1172/JCI111224. View

Smith T, Waterman M . Identification of common molecular subsequences. J Mol Biol. 1981; 147(1):195-7. DOI: 10.1016/0022-2836(81)90087-5. View

10.

Schwartz M . Thymidine phosphorylase from Escherichia coli. Methods Enzymol. 1978; 51:442-5. DOI: 10.1016/s0076-6879(78)51061-6. View

11.

Usuki K, Miyazono K, Heldin C . Covalent linkage between nucleotides and platelet-derived endothelial cell growth factor. J Biol Chem. 1991; 266(30):20525-31. View

12.

Barton G . Protein multiple sequence alignment and flexible pattern matching. Methods Enzymol. 1990; 183:403-28. DOI: 10.1016/0076-6879(90)83027-7. View

13.

Miyazono K, Heldin C . High-yield purification of platelet-derived endothelial cell growth factor: structural characterization and establishment of a specific antiserum. Biochemistry. 1989; 28(4):1704-10. DOI: 10.1021/bi00430a042. View

14.

Barton G, STERNBERG M . A strategy for the rapid multiple alignment of protein sequences. Confidence levels from tertiary structure comparisons. J Mol Biol. 1987; 198(2):327-37. DOI: 10.1016/0022-2836(87)90316-0. View

15.

Desgranges C, Razaka G, Rabaud M, BRICAUD H, Balzarini J, De Clercq E . Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets. Biochem Pharmacol. 1983; 32(23):3583-90. DOI: 10.1016/0006-2952(83)90307-6. View

16.

Finnis C, Goodey A, Courtney M, Sleep D . Expression of recombinant platelet-derived endothelial cell growth factor in the yeast Saccharomyces cerevisiae. Yeast. 1992; 8(1):57-60. DOI: 10.1002/yea.320080106. View