Two-dimensional Electrophoretic Protein Patterns of Reciprocal Hybrids of the Mouse Strains DBA and C57BL

Overview

Journal Biochem Genet

Specialty Molecular Biology

Date 1992 Dec 1

PMID 1296577

Citations 1

Authors

T Vogel

J Klose

Affiliations

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Abstract

Two-dimensional electrophoretic patterns of cytoplasmic liver proteins of the mouse were investigated in reciprocal hybrids of the two inbred mouse strains DBA and C57BL in order to establish whether strain-specific protein variants reveal a mode of inheritance compatible with the concept of genomic imprinting. Variants of this type were found to account for about 11% of approximately 200 variant protein spots scrutinized. Transmission of the maternal form of a variant protein was more frequent than transmission of the paternal form. Maternal/paternal transmission was observed only for proteins showing strain variations in their amount. The results are discussed in terms of the frequency of imprinted genes.

Citing Articles

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PMID: 11934356 PMC: 1690950. DOI: 10.1098/rspb.2001.1911.

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