Tomographic Optical Breast Imaging Guided by Three-dimensional Mammography

Overview

Journal Appl Opt

Date 2003 Sep 10

PMID 12962399

Citations 50

Authors

Ang Li

Eric L Miller

Misha E Kilmer

Thomas J Brukilacchio

Tina Chaves

Jonathan Stott

Quan Zhang

Tao Wu

Maryann Chorlton

Richard H Moore

Daniel B Kopans

David A Boas

Affiliations

Soon will be listed here.

Abstract

We introduce a modified Tikhonov regularization method to include three-dimensional x-ray mammography as a prior in the diffuse optical tomography reconstruction. With simulations we show that the optical image reconstruction resolution and contrast are improved by implementing this x-ray-guided spatial constraint. We suggest an approach to find the optimal regularization parameters. The presented preliminary clinical result indicates the utility of the method.

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