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On the Origin of the Transfer RNA Molecule

Overview
Journal J Theor Biol
Publisher Elsevier
Specialty Biology
Date 1992 Nov 21
PMID 1294846
Citations 59
Authors
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Abstract

Data and arguments are given in favour of the hypothesis that the primitive tRNA molecule may have originated from a direct duplication event involving one of the two halves of the tRNA molecule. It seems that a molecule capable of assuming a hairpin structure was involved as a precursor in this duplication. The two halves of the present tRNAs could, therefore, be considered as paralogous.

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