Gene Transcription in HIV Infection

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2003 Aug 28

PMID 12941394

Citations 16

Authors

Yuntao Wu

Jon W Marsh

Affiliations

Soon will be listed here.

Abstract

Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory proteins, especially Tat and Rev. Both the promoter activity and the function of regulatory proteins require the activity of cellular components, thus the virus remains highly dependent on the metabolic state of the cell. HIV also possesses the unusual capacity to transcribe from non-integrated DNA.

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